MRI accurately detects residual breast tumors after radiofrequency ablation

CHICAGO (Reuters Health) - Results of magnetic resonance imaging (MRI) of the breast after radiofrequency ablation of T1 breast tumors correlate closely with what is seen on histopathological examination after surgical excision, a team from Sao Paolo, Brazil, reported here at the annual meeting of the Radiological Society of North America (RSNA 2008).

Results of MRI in 21 women with T1 invasive ductal carcinomas between 1.0 and 2.0 cm in size were described by Dr. Vanessa S. Vilar of Universidade Federal de Sao Paolo-Escola Paulista de Medicina.

The women underwent MRI one week before radiofrequency ablation and again 3-4 weeks afterward. Tumors were then excised, histopathology was done and results were compared with those seen on MRI.

There was a complete absence of lesion enhancement on MRI in 15 of the 21 patients, and in these women histopathology showed no residual tumor tissue.

In four patients, there was "discontinuous and irregular enhancement" in the area of the excised lesion that was confirmed on histology as residual tumor.

In two patients, there was a large area of enhancement on MRI, which was determined to be viable tumor on histology, Dr. Vilar reported.

"MRI has a high (degree of) efficacy to predict residual lesions or the complete absence of tumor in patients submitted to radiofrequency ablation," Dr. Vilar told meeting attendees.

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