Currently Viewing
Kidney cancer patients make their preference known
June 02, 2012 – Jon Garinn
Considering the Personal and Practical Decisions with Breast Reconstruction
May 25, 2012 – Maureen Salamon
Reconstruction: shopping for a new boob
May 24, 2012 – Kathy LaTour
Need to make a cancer decision: call this number
May 23, 2012 – Kathy LaTour
Waking the dead
May 19, 2012 – Jon Garinn
ASCO 2012 ... the latest in cancer research
May 18, 2012 – Elizabeth Whittington
Breaking news on fertility drugs and childhood cancer?
May 18, 2012 – Katherine Lagomarsino
Young cancer patients feeling a little "Stronger"
May 10, 2012 – Lindsay Ray
Survivors of Tranplantations Should Be Aware of Potential Late Effects
May 08, 2012 – Melissa Weber

Kidney cancer patients make their preference known

BY Jon Garinn
PUBLISHED June 02, 2012
If your doctor asked you to choose between equivalent FDA-approved therapies, you would likely base your decision on a treatment's possible side effects and how they might impact your quality of life, especially if you needed to take that treatment for many months or years. In a new study of patients with metastatic kidney cancer, researchers found that quality of life considerations were significantly more important to patients choosing a treatment than to the doctors prescribing it. In the randomized, double-blinded crossover study, 168 patients received Votrient (pazopanib) for 10 weeks followed by a 14-day break and then Sutent (sunitinib) for 10 weeks, or vice-versa. Nearly two-thirds (70 percent) of patients said they preferred Votrient, compared with 22 percent who preferred Sutent, because they had a better quality of life, which included such factors as less fatigue and soreness of the feet, hands, mouth and throat, as well as fewer treatment interruptions, when taking the drug. Eight percent of patients had no preference. The researchers reported that 60 percent of physicians preferred Votrient, compared with 21 percent who preferred Sutent. About 20 percent of doctors had no preference. Speaking at a press briefing at the 48th annual meeting of the American Society of Clinical Oncology in Chicago, Bernard J. Escudier, MD, of the Institut Gustave Roussy in Villejuif, France, called the results "very surprising." "It was a very significant difference," he told reporters. The study was among the first to consider "how patients feel when they take a drug over many months," something that "isn't reflected in traditional adverse event reporting," Escudier said. Patient-reported outcomes will be increasingly be taken into consideration when determining the effectiveness of particular therapies, he added.
Be the first to discuss this article on CURE's forum. >>
Talk about this article with other patients, caregivers, and advocates in the General Discussions CURE discussion group.

Related Articles

1
×

Sign In

Not a member? Sign up now!
×

Sign Up

Are you a member? Please Log In