Thank you for posting your story. Robert sounds inspirational. Our sympathies go out to you. My family is also now dealing with CUP and we seem to have exhausted any options. We were hoping our visits to Memorial Sloan Kettering would bring some hope. But nothing was offered by them. Could have opted for coin toss (were told it had 50/50 chance of affecting the cancer)of chemo but decided against it, and we seem to have caught it at a late stage. Hoping to find some investigative trials as a last hope. Kind of surprised no discussions here. Anyone know of active CUP discussions on the planet? Thanks.