Kids of Childhood Cancer Survivors at No Greater Risk of Birth Defects
March 14, 2012 – Katherine Lagomarsino
American Cancer Society Complete Guide to Nutrition for Cancer Survivors
March 14, 2012 – Katherine Lagomarsino
LIVESTRONG Cancer Guide and Tracker App for iPad
March 14, 2012 – Jon Garinn
Q&A: Inequities in Cancer Care
March 14, 2012 – Len Lichtenfeld, MD
Drug Approved to Treat Pre-Cancer
March 14, 2012 – Elizabeth Whittington
National Conference on Work and Cancer
March 14, 2012 – Jon Garinn
Gridiron Foes Tackle Cancer Off the Field
March 14, 2012 – Lindsay Ray
Answering Kids' Questions About Cancer
March 14, 2012 – Jane Hill
Will I Inherit the Risk for Cancer?
March 14, 2012 – Jeanne Erdmann
Be Your Own Best Advocate When it Comes to Bladder Cancer
March 14, 2012 – Heather L. Van Epps, PhD
Lives Well Lived: Looking Back
March 14, 2012 – Kathy LaTour
What Defines a Cancer Cluster?
March 14, 2012 – Laura Beil
Mindfulness Made Easy
March 14, 2012 – Don Vaughan
Credible Cancer Websites
March 14, 2012
Tips for Vetting Online Cancer Information
March 14, 2012
Healthcare Law Requires Clinical Trial Coverage
March 14, 2012 – Lena Huang
Treatments in the Pipeline
March 14, 2012 – Lindsay Ray
True Breast Cancer Prevention Requires Looking at Environmental Chemicals
March 14, 2012 – Julia Brody, PhD
The Power of Positive Thinking
March 14, 2012 – Christine Sunderman Russell
Jury Still Out on Vitamin C's Effect on Cancer
March 14, 2012 – Lena Huang
Drug Shortage Crisis Averted, for Now
March 14, 2012
Dealing with Breakthrough Cancer Pain
March 14, 2012 – Lacey Meyer
Comments from Readers
March 14, 2012
Despite Advances, More Work is Needed in Bladder Cancer
March 14, 2012 – Debu Tripathy, MD
Honest Discussions Can Help Ease Kids' Anxiety About Cancer
March 14, 2012 – Jane Hill
For Some, Genetic Counseling Is a Lifelong Necessity
March 14, 2012 – Jeanne Erdmann
Stressed During Cancer Treatment? Try Meditating
March 14, 2012 – Don Vaughan
Finding Reliable Cancer Information Online
March 14, 2012 – Paul Engstrom
News from ASCO: Prostate and Colorectal Cancers
March 13, 2012 – Elizabeth Whittington
Advances in Bladder Cancer Treatment Around the Corner
March 14, 2012 – Heather L. Van Epps, PhD
Turning 10
March 13, 2012 – Kathy LaTour
The Search for Environmental Carcinogens
March 14, 2012 – Laura Beil
Kids of Childhood Cancer Survivors at No Greater Risk of Birth Defects
March 14, 2012 – Katherine Lagomarsino
American Cancer Society Complete Guide to Nutrition for Cancer Survivors
March 14, 2012 – Katherine Lagomarsino
LIVESTRONG Cancer Guide and Tracker App for iPad
March 14, 2012 – Jon Garinn
Q&A: Inequities in Cancer Care
March 14, 2012 – Len Lichtenfeld, MD
Currently Viewing
Drug Approved to Treat Pre-Cancer
March 14, 2012 – Elizabeth Whittington
Gridiron Foes Tackle Cancer Off the Field
March 14, 2012 – Lindsay Ray
Answering Kids' Questions About Cancer
March 14, 2012 – Jane Hill
Will I Inherit the Risk for Cancer?
March 14, 2012 – Jeanne Erdmann
Be Your Own Best Advocate When it Comes to Bladder Cancer
March 14, 2012 – Heather L. Van Epps, PhD
Lives Well Lived: Looking Back
March 14, 2012 – Kathy LaTour
What Defines a Cancer Cluster?
March 14, 2012 – Laura Beil
Mindfulness Made Easy
March 14, 2012 – Don Vaughan
Credible Cancer Websites
March 14, 2012
Tips for Vetting Online Cancer Information
March 14, 2012
Healthcare Law Requires Clinical Trial Coverage
March 14, 2012 – Lena Huang
Treatments in the Pipeline
March 14, 2012 – Lindsay Ray
True Breast Cancer Prevention Requires Looking at Environmental Chemicals
March 14, 2012 – Julia Brody, PhD
The Power of Positive Thinking
March 14, 2012 – Christine Sunderman Russell
Jury Still Out on Vitamin C's Effect on Cancer
March 14, 2012 – Lena Huang
Drug Shortage Crisis Averted, for Now
March 14, 2012
Dealing with Breakthrough Cancer Pain
March 14, 2012 – Lacey Meyer
Comments from Readers
March 14, 2012
Despite Advances, More Work is Needed in Bladder Cancer
March 14, 2012 – Debu Tripathy, MD
Honest Discussions Can Help Ease Kids' Anxiety About Cancer
March 14, 2012 – Jane Hill
For Some, Genetic Counseling Is a Lifelong Necessity
March 14, 2012 – Jeanne Erdmann
Stressed During Cancer Treatment? Try Meditating
March 14, 2012 – Don Vaughan
Finding Reliable Cancer Information Online
March 14, 2012 – Paul Engstrom
News from ASCO: Prostate and Colorectal Cancers
March 13, 2012 – Elizabeth Whittington
Advances in Bladder Cancer Treatment Around the Corner
March 14, 2012 – Heather L. Van Epps, PhD
Turning 10
March 13, 2012 – Kathy LaTour
The Search for Environmental Carcinogens
March 14, 2012 – Laura Beil

Drug Approved to Treat Pre-Cancer

Picato OK'ed to treat precancerous skin lesions.
BY Elizabeth Whittington
PUBLISHED March 14, 2012

Squamous cell carcinoma is the second most common skin cancer, affecting nearly 700,000 people each year in the U.S. Many cases are preceded by rough, scaly patches on the skin called actinic keratoses (AK). Although many people with AK never develop skin cancer, it’s standard to treat all cases of AK to prevent cancer.

“While we know that some actinic keratoses will progress to squamous cell carcinoma, there is no way to predict which ones will or when,” says Ronald Davis, MD, a dermatologist and assistant program director of the Tulane University School of Medicine in New Orleans.

Treatment for AK can include surgery, freezing, creams or photodynamic therapy, a type of light therapy that can span several days.

In late January, a new therapy was approved called Picato (ingenol mebutate), a topical gel that works in just a few days. Ingenol mebutate is the active agent in the sap of the plant Euphorbia peplus, a traditional remedy used for skin lesions. The gel was tested in several phase 3 studies and showed more patients with AK treated with Picato had complete disappearance of the precancerous lesions, although it can cause temporary redness, dryness and swelling. Long-term efficacy and impact on preventing cancer is still unknown.

“Many patients have dozens or even hundreds of these lesions, so being able to treat them all, over a period of a few days, is a significant advance over currently available therapies,” Davis says. “I look forward to evaluating this in my clinical practice and assessing the results in comparison with treatments I presently use.”

Be the first to discuss this article on CURE's forum. >>
Talk about this article with other patients, caregivers, and advocates in the Skin Cancer CURE discussion group.

Related Articles

1
×

Sign In

Not a member? Sign up now!
×

Sign Up

Are you a member? Please Log In