Prepping for Treatment
June 19, 2013 – Kathy LaTour
Children Are Not Little Adults
June 19, 2013 – Laura Beil
Autumn Colbert: A Daughter Undaunted
June 19, 2013 – Don Vaughan
The Power of Positive Thinking
June 19, 2013 – Jane Hill
The Health Hypothesis
June 19, 2013 – Jane Hill
Encouraging Words
June 18, 2013 – Don Vaughan
Andropause & Menopause
June 19, 2013 – Barbara Sadick
Treatment Snapshot
June 19, 2013 – Lacey Marlow
Tracking Down Infections
June 19, 2013 – Charlotte Huff
Susie's Story
June 19, 2013 – Kathy LaTour
Robert A. Kyle, MD
June 19, 2013 – Don Vaughan
Qi Gong May Improve Quality of Life in Breast Cancer Patients
June 19, 2013 – Elizabeth Whittington
And in Health: A Guide for Couples Facing Cancer Together
June 19, 2013 – Katherine Lagomarsino
Finding a Clinical Trial Just Got Easier
June 19, 2013 – Jon Garinn
Renewed Focus on Smoking Cessation
June 19, 2013 – Elizabeth Whittington
The National Race to End Women’s Cancer
June 19, 2013 – Jon Garinn
Genetic Variations Found in ALL Patients of Different Ethnicities
June 19, 2013 – Katherine Lagomarsino
Hospitals Need a Menu Makeover
June 19, 2013 – Len Lichtenfeld, MD
Jolie’s Mastectomy Raises Awareness, Prompts Debate
June 19, 2013 – Lindsay Ray
Cancer Clusters and Congress
June 19, 2013 – Lena Huang
ASCO Updates
June 19, 2013 – Staff Reports
Know Your Options
June 19, 2013 – Carol Marcusen
Transcending Cure with Care
June 19, 2013 – Anne Falgoust Ott
Pipeline
June 18, 2013 – Lindsay Ray
Grapefruit Juice: Forbidden Fruit?
June 19, 2013 – Jeanne Erdmann
Up All Night?
June 19, 2013 – Lacey Marlow
Cancer Overtakes Heart Disease As Leading Cause Of Death In Hispanic Population
June 19, 2013 – Roxanne Nelson
Letters From Readers
June 19, 2013
Message From the Editor
June 19, 2013 – Debu Tripathy, MD
Silver Linings in Caregiving
June 19, 2013 – Jane Hill
Managing Expectations
June 18, 2013 – Barbara Sadick
Mind Over Matters
June 19, 2013 – Don Vaughan
Check Please: Choosing the Best Hospital for Your Cancer Surgery
June 18, 2013 – Charlotte Huff
Heart of the Matter: Cardiac Toxicity
June 17, 2013 – Kathy LaTour
Vital Signs: Recognizing and Managing Distress
June 18, 2013 – Laura Beil
Treating Multiple Myeloma From Every Angle
June 18, 2013 – Heather L. Van Epps, PhD
Prepping for Treatment
June 19, 2013 – Kathy LaTour
Children Are Not Little Adults
June 19, 2013 – Laura Beil
Autumn Colbert: A Daughter Undaunted
June 19, 2013 – Don Vaughan
The Power of Positive Thinking
June 19, 2013 – Jane Hill
The Health Hypothesis
June 19, 2013 – Jane Hill
Encouraging Words
June 18, 2013 – Don Vaughan
Andropause & Menopause
June 19, 2013 – Barbara Sadick
Treatment Snapshot
June 19, 2013 – Lacey Marlow
Tracking Down Infections
June 19, 2013 – Charlotte Huff
Susie's Story
June 19, 2013 – Kathy LaTour
Robert A. Kyle, MD
June 19, 2013 – Don Vaughan
Qi Gong May Improve Quality of Life in Breast Cancer Patients
June 19, 2013 – Elizabeth Whittington
And in Health: A Guide for Couples Facing Cancer Together
June 19, 2013 – Katherine Lagomarsino
Finding a Clinical Trial Just Got Easier
June 19, 2013 – Jon Garinn
Renewed Focus on Smoking Cessation
June 19, 2013 – Elizabeth Whittington
The National Race to End Women’s Cancer
June 19, 2013 – Jon Garinn
Genetic Variations Found in ALL Patients of Different Ethnicities
June 19, 2013 – Katherine Lagomarsino
Hospitals Need a Menu Makeover
June 19, 2013 – Len Lichtenfeld, MD
Jolie’s Mastectomy Raises Awareness, Prompts Debate
June 19, 2013 – Lindsay Ray
Cancer Clusters and Congress
June 19, 2013 – Lena Huang
ASCO Updates
June 19, 2013 – Staff Reports
Know Your Options
June 19, 2013 – Carol Marcusen
Transcending Cure with Care
June 19, 2013 – Anne Falgoust Ott
Pipeline
June 18, 2013 – Lindsay Ray
Grapefruit Juice: Forbidden Fruit?
June 19, 2013 – Jeanne Erdmann
Up All Night?
June 19, 2013 – Lacey Marlow
Cancer Overtakes Heart Disease As Leading Cause Of Death In Hispanic Population
June 19, 2013 – Roxanne Nelson
Letters From Readers
June 19, 2013
Currently Viewing
Message From the Editor
June 19, 2013 – Debu Tripathy, MD
Managing Expectations
June 18, 2013 – Barbara Sadick
Mind Over Matters
June 19, 2013 – Don Vaughan
Check Please: Choosing the Best Hospital for Your Cancer Surgery
June 18, 2013 – Charlotte Huff
Heart of the Matter: Cardiac Toxicity
June 17, 2013 – Kathy LaTour
Vital Signs: Recognizing and Managing Distress
June 18, 2013 – Laura Beil
Treating Multiple Myeloma From Every Angle
June 18, 2013 – Heather L. Van Epps, PhD

Message From the Editor

Think about the long-term consequences of cancer treatment.

BY Debu Tripathy, MD
PUBLISHED June 19, 2013

In this issue, we cover an important topic that often takes a back seat to the discussions and decisions about cancer treatment: the collateral damage these treatments can cause—the same treatments that over the years are continuing to improve the outlook for many cancer patients.

Even though therapies are becoming more focused on cancer cells (and not healthy tissue) through the advent of a new generation of targeted agents, we still rely on chemotherapy, the most commonly used class of drugs for many types of cancer. Even biologically targeted "magic bullet" drugs can be off target or can share targets with healthy cells. Most damaged normal cells and tissues repair themselves through natural healing, regeneration and recovery, but some effects from treatment can be long-standing—even permanent. You will read about several aspects of these long-standing or permanent effects that are part of what is termed "survivorship" concerns. Although permanent effects tend to be rare compared with the more common and well-known short-term side effects, the permanent effects need to be understood by both the care team and the patient.

Although permanent effects tend to be rare compared with the more common and well-known short-term side effects, the permanent effects need to be understood by both the care team and the patient.

One not-so-rare permanent side effect is infertility, and this is relevant for the nearly 10 percent of people in the U.S. who receive a cancer diagnosis under the age of 45 (Read "Preserving Fertility"). Another side effect that is not fully understood is cardiac toxicity, a spectrum of disorders that can affect the heart in different ways and can be transient or permanent depending on the treatment and patient factors. Both of these topics are discussed in detail in thought-provoking articles (Read "Cardiac Toxicity: Heart of the Matter"). The "thought-provoking" aspect is important because every cancer patient needs to be fully aware of possible consequences of treatment to make a more informed, value-based decision and know what to monitor and report to the care team. The encouraging trend is that, in many cases, new methods are available to prevent these side effects, to detect and treat them, and to determine who might be more at risk for experiencing them.

Debu Tripathy, MD

Editor-in-Chief
Professor of Medicine, University of Southern California
Co-Leader, Women’s Cancer Program at the USC/Norris Comprehensive Cancer Center

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