Brian Koffman, MDCM, MSEd, provides insight from a patient’s perspective on self-advocacy and reflects on the positive direction in which the treatment paradigm of chronic lymphocytic leukemia (CLL) is heading.
Brian Koffman, MDCM, MSEd, shares insight on his current relapse of chronic lymphocytic leukemia (CLL) and discusses the potential value of chimeric antigen receptor (CAR) T-cell therapy, which he will be receiving in an upcoming clinical trial.
Brian Koffman, MDCM, MSEd, discusses his rejection of allogeneic stem cell transplant and development of chemorefractory chronic lymphocytic leukemia (CLL) that led to his participation in an early clinical trial of ibrutinib.
Never in their wildest dreams dreams would immunologists from the last generation have imagined chimeric antigen receptor (CAR)-T cell therapy coming to light. The very notion of genetically engineering a T cell to recognize a tumor antigen would have been viewed almost as a pipe dream.