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Study shows how to prevent rash from EGFR inhibitors

BY MELISSA WEBER | JUNE 1, 2009

If you're receiving an EGFR inhibitor to treat your cancer, I have some good news. Doctors now know how to prevent the skin rash that develops in up to 90 percent of patients receiving these drugs.

A combination of sunscreen, moisturizers, topical corticosteroids, and the oral antibiotic doxycycline reduced the incidence of severe rash by more than half when given to patients before Vectibix, compared with patients who were treated after the rash developed. The study was reported today at ASCO's annual meeting, and presenter Edith Mitchell, MD, of Thomas Jefferson University in Philadelphia, told reporters that her institution has already implemented the rash prevention strategy. Check out the article we ran in the magazine for all the details about this side effect.

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COMMENTS

I would like to know if there is anyone in Owensboro,Kentucky that has multiple myeloma that I can talk too. Thank You, Brenda
- Posted by Brenda Porter 6/12/09 2:20 PM

I was diagnosed with Multiple Myeloma and was treated. I have been in complete remission for 2.4 years. I would be glad to answer any questions Brenda may have regarding MM and its treatment.
- Posted by N Winslow 6/12/09 4:56 PM

I began taking Tarceva on June 12th & read about the EGFR inhibitor within days. My doctor prescribed the doxyclinine on Mon. June 15th & I began the combination of creams regimen. But.....my concern is.....if it prevents the rash, how will I know if the Tarceva is working?
- Posted by Ginny Brown 6/18/09 6:30 AM

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