For some patients, multiple myeloma can progress in severity and over time the disease can become resistant to treatment with many approved therapies. For these patients, it is important to be seen by a myeloma specialist who can provide the most updated information on new treatments and clinical trials that may be appropriate for them.

For many, multiple myeloma can be managed like a chronic condition, with medicine given for years. Others who have no detectable cancer after initial treatment for myeloma may move forward without medication unless their disease recurs.

Symptoms such as bone pain and loss, kidney problems, anemia and infection may interfere with everyday life and require palliative treatment. For many patients, involvement of the bone may cause lost height or change the curvature of the spine.