Clinical Trial Corner

Expansion of IOA-244 Trial Fully Enrolled for Uveal Melanoma

November 26th 2021, 10:00pm


Part B of the DIONE-01 study will look at whether IOA-244 increases anti-tumor responses in expansion groups of patients.

Phase 2 Trial Initiated for Second Line Treatment of AML and MDS

November 18th 2021, 12:00am


A phase 2 trial of aspacytarabine (BST-236) was initiated in patients with AML and MDS.

CAR-T Cell Therapy Trial Currently Enrolling Patients With CLL and SLL

November 16th 2021, 12:00am


The TRANSCEND CLL 004 trial is currently enrolling patients to determine the efficacy of a CAR-T cell therapy.

First Patient Receives Novel Immunotherapy in Bladder Cancer Sub-Study

November 13th 2021, 10:00pm


The first patient with bladder cancer was dosed in a phase 1/2 trial examining responses to an investigational immunotherapy.

Enrollment Begins in Devimistat Trial for Patients With Relapsed Clear Cell Sarcoma

November 12th 2021, 12:00am


The first patient has been enrolled in the APOLLO 613 Phase 1/2 clinical trial for CPI-613.

Study Initiated for Bispecific Antibody in Patients With T-cell Lymphoma

November 10th 2021, 12:00am


A phase 1 trial of ONO-4685 was initiated for the evaluation of the antibody in patients with relapsed or refractory t-cell lymphoma.

BOLD-100 Trial Receives FDA Clearance for Treatment of Advanced GI Cancers

November 4th 2021, 11:00pm


The Food and Drug Administration gave clearance to Bold Therapeutics for a phase 1b/2a trial examining treatments for advanced GI cancers.

Patients Dosed in Trial of Topical Gel for Dose-Limiting Acneiform Lesions in Patients With Colorectal Cancer

November 1st 2021, 11:00pm


The first patients were dosed in a phase 2 trial for a topical gel to treat lesions in patients with colorectal cancer receiving EGFR inhibitor therapy.

Clinical Trial Launched for Preventive Breast Cancer Vaccine

October 28th 2021, 11:00pm


Cleveland Clinic’s Lerner Research Institute has initiated a new study to examine a vaccine to prevent triple-negative breast cancer.

New Trial Initiated for Fosciclopirox in Patients With Bladder Cancer

October 26th 2021, 11:00pm


A phase 1b trial started to study the effects of fosciclopirox in patients with newly diagnosed and recurrent bladder cancer.