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Rare Cancers | Tumor

CURE’s rare cancers page is a go-to resource for oncology news and updates in the world of rare cancers Here, readers will find cancer articles, videos, podcasts, and more with expert insight into the latest treatments and research in rare cancers.

Drug Duo Represents ‘Potential Paradigm Shift’ for Rare Eye Cancer

April 25th 2023

Darovasertib plus Xalkori is showing promise for the treatment of patients with metastatic uveal melanoma, according to results from an ongoing study.

HPV Causes Multiple Cancers, Though Knowledge on the Connection Is Lagging

April 18th 2023

HPV vaccination rates and public knowledge about the connection between the virus and certain cancer types are below what they should be, research found.

Remaining Positive Amidst a Stage 4 Rare GI Cancer Diagnosis

April 14th 2023

After being given 2 years to live by her oncologist, a mother of two children is trying her best to protect her family — and herself — from thinking too negatively despite having rare gastrointestinal cancer.

FDA Approves Zynyz for Subset of Patients With Rare Skin Cancer

March 22nd 2023

This FDA approval of Zynyz was based on findings from a study which demonstrated that the therapy improves responses in patients with locally advanced Merkel cell carcinoma.

Enhertu Provides Meaningful, Durable Responses in HER2-Expressing Solid Tumors

March 14th 2023

The phase 2 DESTINY-PanTumor02 trial included patients with HER2-expressing solid tumors such as bladder, pancreatic and rare tumors.

'Ugly Blessings’ and Blooming From Cancer’s Lessons

March 8th 2023

After being diagnosed with a rare cancer, I met some amazing people and have a new appreciation for life.

Dealing With Life-Changing Cancer My Own Way

March 5th 2023

When I sit down with my paint brush, despite my cancer history, I don’t feel different anymore.

I Wish I Advocated More When Doctors Told Me I Didn’t Have Cancer

February 27th 2023

On multiple occasions, doctors told me not to worry, but I ended up being diagnosed with a rare cancer called leiomyosarcoma.

Novel Drug to Be Tested in Rare Form of Eye Cancer

January 24th 2023

A phase 2 study will investigate the efficacy of darovasertib for patients with uveal melanoma and whether the drug can potentially result in lower radiation doses or fewer eye removal surgeries.

Lytogbi Continues to Improve Cholangiocarcinoma Outcomes

January 20th 2023

Lytgobi was approved for pretreated cholangiocarcinoma in September, and updated study findings support the drug’s continued approval.

Welireg Made a von Hippel-Lindau Survivor Feel Like a 'Medical Miracle'

December 15th 2022

When Sean Korbitz was a 20-year-old college student, his life trajectory changed with a rare cancer diagnosis, resulting in the removal of 40 tumors; fifteen years later, a new drug made him feel like a “medical miracle.”

A Look at the ‘Collateral Damage’ From Uveal Melanoma Treatment

December 14th 2022

From eye removal to radiation damage, patients with uveal melanoma may face complications after treatment, although continued and new therapies may address these issues, an expert said.

FDA Approves Tecentriq for Rare Sarcoma Subtype in Adults and Children

December 12th 2022

Tecentriq was approved by the FDA for adults and children aged two years and older with advanced alveolar soft part sarcoma, a disease typically diagnosed in approximately 80 patients per year in the U.S.

Creating a Charity 8 Days After a Rare Cancer Diagnosis: Dying Defiantly Founder Shares His Story

December 8th 2022

After Marshall Morris was diagnosed with a rare cancer and given only six months to live, he created a charity that empowers people with terminal illness and provides them with counseling and support.

'A Village of People’ May Help Cancer Caregivers Balance Everyday Life

November 23rd 2022

A woman whose husband was diagnosed with ocular melanoma at 28 years old opens up about her experiences navigating the cancer world and her search for a supportive community.

Clinical Trial Kicks Off Evaluating a New Drug for a Group of Solid Cancers

November 4th 2022

A novel drug, MRT-2359, will be studied in a phase 1/2 trial for patients with MYC-driven cancers.

Cancer Survivor Throws Out World Series First Pitch, Dwayne ‘The Rock’ Johnson Sends Best Wishes to Child With Brain Cancer and More

November 4th 2022

From a childhood cancer survivor throwing out the first pitch at Game 4 of the World Series to former WWE champion and actor Dwayne “The Rock” Johnson recording a message for a child with brain cancer, here’s what’s happening in the cancer space this week.

Ocular Melanoma Advocacy Groups Provide Wealth of Information to Patients, Caregivers on This Rare Cancer

October 26th 2022

Advocacy groups helped one patient with ocular melanoma — and many others — learn more about their disease and treatment, as well as a place to connect about their experiences.

What It’s Like to Navigate Vaginal Cancer, a Rare Type of Gynecological Cancer

October 24th 2022

Vaginal cancer is amongst the rarest of gynecologic cancer, it is important those patients with a rare cancer advocate for themselves and find doctors who are experts in treating it.

Multi-Chemotherapy Regimen Elicits Improved Outcomes in Rare Form of Pediatric Lung Cancer, But More Research is Needed

October 6th 2022

The use of a multi-agent chemotherapy regimen resulted in improved outcomes in a group of children with pleuropulmonary blastoma, a rare form of lung cancer, when compared with other regimens.

Many Survivors of GISTs, a Rare Cancer, May Experience Cancer-Related Cognitive Impairments After Treatment

October 5th 2022

Nearly two thirds of patients with GISTs — a rare type of cancer that often begins in the digestive system — indicated that their overall quality of life after treatment had been affected by cancer-related cognitive impairments, also referred to as “chemo brain,” according to analysis of survey data.

Bringing Clarity to Ocular Melanoma: Patient Advocate Offers Ways Support Can Help Patients, Loved Ones

September 30th 2022

Melody Burchett, of A Cure In Sight, discussed the value of seeking support after an ocular melanoma diagnosis, and how such help can be found in others with the same diagnosis.

FDA Approves Lytgobi for Advanced Cholangiocarcinoma

September 30th 2022

The Food and Drug Administration approved Lytgobi for patients with previously treated advanced cholangiocarcinoma with FGFR2 gene rearrangements.

Adding a Certain Immunotherapy Drug to Chemotherapy May Benefit Patients With Thymoma, a Type of Rare Cancer

September 26th 2022

The addition of Bavencio to an Inlyta regimen may help stabilize disease in some patients with thymic carcinoma, but one expert stressed that checkpoint inhibitors are “problematic” for patients diagnosed with thymoma, a type of rare cancer.

Uveal and Skin Melanoma Share a Common Name, But That’s The Only Similarity, Says Expert

September 21st 2022

Melanoma of the skin has been shown to be greatly associated with exposure to sunlight, whereas uveal melanoma — commonly known as cancer of the eye — is not.

FDA Issues Statement on New Cases of Rare Breast Implant-Related Cancers

September 9th 2022

The Food and Drug Administration issued a statement about the incidence of new cases of rare cancers that have occurred in the scar tissue around breast implants.

Treatment for a Rare Form of Eye Cancer Has Shifted From Removing the Eye to Preserving Vision and Extending Lives, Says Expert

September 1st 2022

An expert provides insight on how primary uveal melanoma is often treated and sheds some light on an unmet need in treating the eye cancer.

Early Findings of Novel Agent Show Promise in Treating Rare Blood Cancer

August 31st 2022

Patients with blastic plasmacytoid dendritic cell neoplasms can enroll in the ongoing CADENZA trial, which is investigating the safety and efficacy of the novel agent pivekimab sunirine in patients with the rare blood cancer.

Imfinzi-Novel Drug Combination Elicits Effective Responses in a Group of Patients With Metastatic Sarcomas

August 10th 2022

Treatment with a combination of Imfinzi and the novel drug tremelimumab demonstrated promising results in certain patients with advanced or metastatic sarcoma, which are rare cancers of the bone and soft tissue.

What Is Uveal Melanoma?

July 27th 2022

Here is a breakdown of some of the important information surrounding uveal melanoma, an extremely rare form of cancer.

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