Rare Cancers

Mohs micrographic surgery offered better survival outcomes for patients with early-stage Merkel cell carcinoma, compared with wide local excision.

Merkel cell carcinoma made headlines with the death of Jimmy Buffett. It’s rare and dangerous, and cases are becoming more common.

"Margaritaville" singer-songwriter Jimmy Buffett died four years after receiving a diagnosis of Merkel cell carcinoma that "can be really nasty," one expert tells CURE.

I faced cancer thrice and chose life each time — not because of some flowery will to live, but because I’m stubborn and wanted to prove that cancer is not the boss of me.

Here’s a look back at the therapies for solid cancers that gained FDA approval this summer.

The Hepzato Kit is a direct-to-liver therapy for patients with uveal melanoma with hepatic metastases.

Certain patients with penile squamous cell carcinoma responded to therapy with an immune checkpoint inhibitor, according to recent research.

Using inter-arterial chemotherapy compared to intravenous chemotherapy may significantly improve globe salvage rates in children with advanced unilateral retinoblastoma.

A new study identified the elements that could determine the overall survival of patients with the metastatic eye tumor, uveal melanoma.

An expert gives an overview of the treatment options for uveal melanoma, and why he considers hope to be an essential part of the care plan.

Darovasertib plus Xalkori is showing promise for the treatment of patients with metastatic uveal melanoma, according to results from an ongoing study.

HPV vaccination rates and public knowledge about the connection between the virus and certain cancer types are below what they should be, research found.

After being given 2 years to live by her oncologist, a mother of two children is trying her best to protect her family — and herself — from thinking too negatively despite having rare gastrointestinal cancer.

This FDA approval of Zynyz was based on findings from a study which demonstrated that the therapy improves responses in patients with locally advanced Merkel cell carcinoma.

The phase 2 DESTINY-PanTumor02 trial included patients with HER2-expressing solid tumors such as bladder, pancreatic and rare tumors.

After being diagnosed with a rare cancer, I met some amazing people and have a new appreciation for life.

When I sit down with my paint brush, despite my cancer history, I don’t feel different anymore.

On multiple occasions, doctors told me not to worry, but I ended up being diagnosed with a rare cancer called leiomyosarcoma.

A phase 2 study will investigate the efficacy of darovasertib for patients with uveal melanoma and whether the drug can potentially result in lower radiation doses or fewer eye removal surgeries.

Lytgobi was approved for pretreated cholangiocarcinoma in September, and updated study findings support the drug’s continued approval.

When Sean Korbitz was a 20-year-old college student, his life trajectory changed with a rare cancer diagnosis, resulting in the removal of 40 tumors; fifteen years later, a new drug made him feel like a “medical miracle.”

From eye removal to radiation damage, patients with uveal melanoma may face complications after treatment, although continued and new therapies may address these issues, an expert said.

Tecentriq was approved by the FDA for adults and children aged two years and older with advanced alveolar soft part sarcoma, a disease typically diagnosed in approximately 80 patients per year in the U.S.

After Marshall Morris was diagnosed with a rare cancer and given only six months to live, he created a charity that empowers people with terminal illness and provides them with counseling and support.

A woman whose husband was diagnosed with ocular melanoma at 28 years old opens up about her experiences navigating the cancer world and her search for a supportive community.