Head & Neck Cancer | Tumor

CURE’s head & neck cancer page is a go-to resource for oncology news and updates in the world of head & neck cancer Here, readers will find cancer articles, videos, podcasts, and more with expert insight to the latest treatments and research in head & neck cancer.

‘Duran Duran’ Guitarist Misses Hall of Fame Induction Due to Cancer, ‘Yellowstone’ Actor Discusses His Diagnosis and More

November 11th 2022

From the singer of “Duran Duran” revealing his stage 4 cancer diagnosis — and missing the band’s induction to the Rock & Roll Hall of Fame because of it — to Barry Corbin’s oral cancer fears, here’s what’s happening in the oncology space this week.

Trial to Investigate if a Novel Drug Can Foster Keytruda Effectiveness in Solid Cancers

October 11th 2022

NC410 plus Keytruda will be studied in a phase 1b/2 trial for patients with certain solid cancers that either did not respond to or have not been treated with an immunotherapy agent.

FDA Fast Tracks Investigational Drug With or Without Keytruda for Possible Approval for Head and Neck Cancer

October 10th 2022

The FDA granted a fast track designation to an investigational drug alone and in combination with Keytruda to treat patients with HPV recurrent/metastatic head and neck squamous cell carcinoma.

Active Surveillance ‘Most Definitely’ a Viable Treatment Option for Some Patients with Thyroid Cancer, Says Expert

September 29th 2022

Compared with surgery, active surveillance was just as effective and lowered anxiety levels in patients with low-risk papillary thyroid cancer.

Early-Phase Trial to Study Novel Drug, With or Without Keytruda, in Solid Cancers

September 27th 2022

The novel drug PY159 will be studied as a single agent and in combination with Keytruda for patients with certain solid tumors — including ovarian, pancreatic, lung, head and neck, colorectal and breast cancers.

A Shift in Focus for Head and Neck Cancer Treatment

September 20th 2022

Years ago, the goal of head and neck cancer treatment was strictly focused on a cure. Now, there has been a slight change in approach to improve survival rates while preserving quality of life.

Keytruda Treatment Regimen Misses Survival Goal in Head and Neck Cancer

July 20th 2022

The addition of Keytruda to chemoradiation, followed by maintenance Keytruda, did not lead to a statistically significant event-free survival benefit in patients with locally advanced head and neck squamous cell carcinoma.

Trial Launched to Analyze Safety of Novel Drug to Treat Severe Side Effect that Occurs in Approximately Half of Patients With Advanced Cancer

July 15th 2022

The first patient enrolled onto a phase 1 trial has received TCMB07, an investigational drug, for the treatment of cachexia, a severe disorder that may occur in more than half of patients with advanced-stage cancer.

Study of Novel Drug Combo in Head and Neck Cancer Closed After Several Patient Deaths

July 12th 2022

A clinical trial reviewing the safety and efficacy of a treatment regimen of enoblituzumab in combination with either retifanlimab or tebotelimab in patients with recurrent or metastatic squamous cell carcinoma of the head and neck has been stopped by the manufacturer of the cancer drugs.

5 FDA Cancer Drug Approvals for Solid Tumors That Patients May Have Missed

June 29th 2022

Here is a roundup of cancer treatments that were approved by the FDA in the spring of 2022 that patients may have missed.

I'm a Cancer Survivor... What Now?

June 15th 2022

Although much has changed in the past two decades, more needs to be done to prepare cancer survivors for what happens after their treatments end.

New Drug May Mitigate Incidence, Severity of Chemotherapy-Related Oral Mucositis in Patients With Head and Neck Cancer

June 4th 2022

Avasopasem manganese is the first drug that has been shown to reduce the incidence and severity of chemotherapy-related oral mucositis in patients with head and neck cancer, research showed.

FDA Fast Tracks Novel Immunotherapy-Keytruda Combo for HPV-Related Head and Neck Cancer

June 2nd 2022

The Food and Drug Administration granted a fast track designation to PDS0101 plus Keytruda for the treatment of patients with recurrent or metastatic HPV16-related head and neck cancer.

Oncology Rehabilitation: An Integral Part of Integrative Care for Head and Neck Cancer Treatment

May 26th 2022

Head and neck cancer treatments and the subsequent side effects can be overwhelming for patients and their caregivers due to the impact they have on routine activities, writes a speech-language pathologist at Cancer Treatment Center of America Atlanta. However, the expert notes, there are plenty of specialists who can help improve patient quality of life.

FDA Rejects Request to Approve Novel Drug-Chemo Combo to Treat Head and Neck Cancer

May 10th 2022

The manufacturers of the drug plan to resubmit the request for the FDA to approve the regimen sometime this summer.

Newfound Sense of Empathy Makes Cancer Survivor ‘Feel More Human’

April 8th 2022

After surviving cancer and the many bad days that come with a diagnosis, voice actor Rob Paulsen noted that he had a newfound sense of empathy that helped him out of some of his darkest days.

‘Authentically Empathic’ Late-Stage Patient Inspires Fellow Cancer Survivor

March 28th 2022

When lovers of “Pinky and the Brain,” “Teenage Mutant Ninja Turtles” and other cartoons gathered in voice actor Rob Paulsen’s hospital room, he took particular notice of one exuberant woman with cancer who was extroverted and kind, despite not having long to live.

Potential FDA Cancer Drug Approvals on the Horizon This Spring

March 24th 2022

The Food and Drug Administration plans on reviewing multiple new cancer therapies this spring.

Personalized Treatment Advanced the Field and Decreased Side Effects in Head and Neck Cancer

March 24th 2022

Over the last 20 years, head and neck cancer treatment moved away from aggressive treatments for all patients to a more personalized approach — improving both outcomes and quality of life for patients with the disease.

Trial to Assess Safety and Efficacy of Novel Drug for Extremely Rare Cancer Begins Enrolling Patients

March 10th 2022

The rare cancer, known as adenoid cystic carcinoma, is diagnosed in fewer than 1,500 people in the United States each year and is often found in the salivary glands, a part of the body associated with helping a person swallow and digest food.

Decades' Worth of Reconstruction Advancements Have Transformed the Lives of Many Patients Who Underwent Debilitating Cancer Treatments

March 10th 2022

Aesthetic appearances, according to an expert at the UCSF, are often important for patients following the surgical treatment of cancer. Advancements in this space over the past 20 years have allowed many to patients to look as normal as possible.

Some Patients With Oropharynx Cancer May Be Eligible to Decrease Radiation Treatment and Curb Side Effects

February 25th 2022

The use of PET imaging midway through oropharynx treatment may help identify patients who can de-escalate their radiation without compromising tumor control.

Photoimmunotherapy Trial Begins in Certain Patients With Head and Neck, and Skin Cancer

February 22nd 2022

The goal of the phase 2 trial is to study the safety and efficacy of ASP-1929, a photoimmunotherapy with fluorescence imaging, in patients with head and neck or skin cancer.

Expert Sheds Light on Ways Patients With Cancer and Impaired Eating Function Can Approach Social Situations

February 11th 2022

A speech and swallowing specialist recommends that patients with head and neck cancer who have difficulties chewing and swallowing food eat before attending social situations to mitigate anxiety about eating around others.

Trial Underway for Novel Agent Plus Immunotherapy for HPV-Related Head and Neck Cancer

February 2nd 2022

After preliminary results showed promise for the combination, researchers are expanding their clinical trial for PDS0101 plus Keytruda in HPV-related head and neck cancer.

Reduced Radiation Dose After Surgery May Improve Survival Rates in HPV-Related Throat Cancer

January 12th 2022

A recent study demonstrated that a lower dose of radiation after surgery for HPV-related throat cancer may provide a greater benefit than a higher dose of radiation with chemotherapy.

Trial Launched to Assess Safety and Efficacy of Novel Drug in Rare Type of Head and Neck Cancer

January 10th 2022

A phase 2 trial was recently launched to examine the safety and efficacy of oral inhibitor VK-2019 in patients with advanced Epstein-Barr Virus-positive nasopharyngeal carcinoma, a rare type of head and neck cancer, and lymphoma.

Voice Actor Discusses the ‘Platinum Lining’ Behind His Throat Cancer Diagnosis

July 30th 2021

Rob Paulsen is the voice behind many beloved cartoon characters, but after receiving a cancer diagnosis, he discovered a whole new way to relate to others.

‘On the Rise:’ Immunotherapy Options for Head and Neck Cancer

June 21st 2021

On behalf of the Head and Neck Cancer Alliance, Dr. Michael Moore spoke with CURE® about emerging therapies that potentially offer exciting new options for the future.

Novel Drug-Chemo Combo Significantly Improves Survival in Rare Form of Head and Neck Cancer

June 5th 2021

The addition of a novel drug to the chemotherapies gemcitabine and cisplatin significantly improved a survival outcome in patients with a rare form of head and neck cancer, compared with chemotherapy alone.