Currently Viewing
Another Lesion: LCIS
September 25, 2014 – Charlotte Huff
The Benefits of Personal Training
September 25, 2014 – Jane Hill
A Controlling Nature Can Take a Toll on a Caregiver
September 25, 2014 – Don Vaughan
What to Know Before You Go
September 25, 2014 – Jeanne Erdmann
Early Detection is Key
September 25, 2014 – Sonya Collins
Caregivers Can Benefit From Early Intervention
September 25, 2014 – Kathy LaTour
On the Web: End of Life Care
September 24, 2014
Beginning the Conversation
September 24, 2014 – Kathy LaTour
Advocating for your loved one at the end of life
September 24, 2014 – Kathy LaTour

Another Lesion: LCIS

Lobular carcinoma in situ, or LCIS, is considered a risk factor for invasive cancer. 

BY Charlotte Huff
PUBLISHED September 25, 2014

Lobular carcinoma in situ, or LCIS, sounds similar to its linguistic cousin DCIS (ductal carcinoma in situ). But its diagnosis is typically considered less worrisome.

Rather than being a precancerous lesion like DCIS, the lobular lesion is considered only a marker of elevated risk for invasive cancer down the road, according to the National Cancer Institute. Irene Wapnir, chief of breast surgery at Stanford School of Medicine in Stanford, Calif., explains that doctors approach LCIS as a high-risk lesion, unlike DCIS, which is regarded as a cancerous lesion that requires breast biopsy and then either lumpectomy with radiation or mastectomy.

[Read more about DCIS]

In some cases of LCIS, surgery might be recommended: for example, if the LCIS is scattered throughout the breast, Wapnir says. But for most women, taking the estrogen blockers tamoxifen or raloxifene is the recommended approach. In one large-scale prevention study, which included 830 women with a history of LCIS, use of tamoxifen reduced the risk of later developing an invasive cancer by more than half.

Be the first to discuss this article on CURE's forum. >>
Talk about this article with other patients, caregivers, and advocates in the Breast Cancer CURE discussion group.

Related Articles


Sign In

Not a member? Sign up now!

Sign Up

Are you a member? Please Log In