Fall 2006

Letters from Our Readers

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CURE's Survivors special issue, treatment side effects, treating renal cell carcinoma, and a survivor's map.

Deciding between complex cancer treatment options can be overwhelming, and each choice has pros and cons, but following a few tips of advice may ease the decision-making process

The Shadow Survivors

A childhood cancer diagnosis often makes well siblings feel like they’re battling the disease too.

Deep in the bone marrow lies the reason for blood disorders classified as myelodysplastic syndromes—stem cells gone awry.

Fatal Fibers

Asbestos exposure is the main cause of mesothelioma, accounting for more than 80 percent of cases.

Experts recommend bereaved caregivers find a routine after a loved one’s death, either by returning to work or setting up another type of schedule instead of being home alone in order to escape from the grief.

Reentering the workforce after a cancer diagnosis can add anxiety to an already stressful job hunt and whether a survivor chooses to disclose a diagnosis or not, there are a few helpful guidelines to consider.

Lymphedema can develop as a result of removing or destroying lymph nodes during surgery or radiation, causing arm heaviness and swelling, but research shows that exercise, lymph drainage, compression and protection helps manage lymphedema and alleviate symptoms.

Sisterhood

Some siblings may take on a parental role while others become advocates, but individual reactions to a cancer diagnosis vary greatly, depending the sibling relationship and the sibling’s age at diagnosis

Many experts consider lobular carcinoma in situ, LCIS, to be a precursor to invasive breast cancer, but there is still debate over the best treatment including surgery and prevention with tamoxifen or Evista.

The risks and benefits of mammography screening vary by age—the benefit for women over age 50 has been proven, but debate continues about the benefit of screening younger women, beginning at age 40.

The Scoring System

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Researchers designed the Van Nuys Prognostic Index to aid in treatment decisions for women diagnosed with ductal carcinoma in situ, DCIS.

Improvements in the classification of myelodysplastic syndrome, MDS, based on varying characteristics in the disease have better defined prognosis and helped patients and doctors make treatment-related decisions.

Allogeneic stem cell transplantation and improvements in conditioning treatments may make transplant available to more patients and lower risk of severe side effects.

About 20 percent of patients develop secondary MDS—when the disease is caused by chemotherapy, such as alkylating agents, or radiation used to treat a previous cancer—and current research is focused on finding genetic alterations that will provide better treatment options for these patients.

House Call

Dr. Aman Buzdar discusses the latest breast cancer treatment strategies with aromatase inhibitors.