Overall survival in metastatic gastric or gastroesophageal junction cancer improved significantly in patients who received the oral combination chemotherapy Lonsurf regardless of whether they’d had a gastrectomy.
Nearly half of patients with a particular type of cholangiocarcinoma responded to a combination of two targeted drugs — Tafinlar (dabrafenib) and Mekinist (trametinib), which together inhibit the growth-signaling proteins BRAF and MEK in patients with different types of rare cancers that carry the BRAF V600E gene mutation.
The Food and Drug Administration (FDA) has granted a priority review to a supplemental new drug application for Lonsurf (TAS-102; trifluridine/tipiracil) for use in previously treated patients with advanced or metastatic gastric adenocarcinoma, including cancer of the gastroesophageal junction.
Immunotherapy pioneers James P. Allison, Ph.D., and Tasuku Honjo, M.D., Ph.D., have won the 2018 Nobel Prize in Physiology or Medicine for their research that eventually led to the use of immune checkpoint inhibitors to treat cancer.
While having a career as a flight attendant allows individuals to travel the globe, exposure to carcinogens and frequent disruptions in circadian rhythms may increase cancer prevalence in these individuals, according to recent research published in the journal Environmental Health.
But just what information is most useful to patients with NETs, and where are the gaps in the educational and supportive resources to which they have access? A study – presented at the Gastrointestinal Cancers Symposium on Jan. 19, in San Francisco – explored just that.