Video

Deciding Best Next Steps in Prostate Cancer Treatment

Author(s):

Matthew R. Cooperberg, M.D., M.P.H.

Here's how one expert decides on the next steps in treatment when a man with prostate cancer has a rising PSA and no visible metastases.

There is no standard protocol for treating men with prostate cancer who are on hormonal therapy and have a rising PSA, but no signs of metastasis.

When deciding on the next line of treatment, Matthew R. Cooperberg, M.D., M.P.H., associate professor and Epidemiology & Biostatistics Helen Diller Family Chair in Urology at UCSF, said that he looks at the details: What is the patient's Gleason score, prior treatments and other aggressive characteristics of the disease?

This group of patients will likely require more systemic treatment with novel agents. Patients and physicians should discuss risks, treatment side effects and the cancer's aggressiveness when deciding when it is the right time to start, says Cooperberg.

Related Videos
Image of a woman with tied back hair, wearing pearl earrings.
Image of a woman with layered hair, wearing a bright blue cardigan.
Image of a man with short black hair.
Image of man with gray hair.
Image of woman with black hair.
Image of a man wearing a black suit and tie.
Image of a man with white hair and a white goatee.
Image of a woman with brown wavy hair, wearing a navy blue top.
Image of a man wearing a suit with a red bowtie.
Related Content
Image of a doctor talking with a male patient.
October 23rd 2024

Testosterone Recovery in Prostate Cancer May Depend on ADT Intensity

Ashley Chan
Patients with prostate cancer may differ in time to testosterone recovery, depending on the length of treatment and age, but takes six months on average.
Image of CURE's Cancer Horizons podcast logo: a white microphone with yellow noise lines. Highlights from the 2024 ASCO gastrointestinal and genitourinary cancer conferences.
January 30th 2024

Highlights from the Gastrointestinal and Genitourinary Cancer Conferences

Alex Biese Brielle Benyon
Here are some of the top stories from the recent Gastrointestinal Cancers Symposium as well as the Genitourinary Cancers Symposium.
Image of PSA test.
October 21st 2024

Rise in PSA Levels May Predict Treatment Response in Prostate Cancer

Spencer Feldman
The rate at which PSA rises after hormonal therapy for prostate cancer is a key factor in determining the effectiveness of the treatment.
CURE Cancer Horizons podcast logo
January 29th 2024

Prostate Cancer Headlines, CAR-T Warnings and Laughter Therapy

Alex Biese Brielle Benyon
CURE® editors discuss last week’s biggest cancer headlines, from Dexter Scott King’s death to the potential of laughter therapy to boost quality of life.
Image of doctor consulting man.
October 16th 2024

Next-Generation Imaging a ‘Gold Standard’ in Metastatic Prostate Cancer

Ashley Chan
Patients with metastatic prostate cancer may have improved survival outcomes after undergoing next-generation PSMA PET imaging, an expert explained.
Image of researchers doing lab tests.
October 15th 2024

Why ‘Genetic Testing is Critical’ in Patients with Prostate Cancer

Alex Biese
As part of the CURE® Educated Patient® Prostate Cancer Summit, an expert discussed the role genetic testing plays in treatment decision-making for many.