Video

Introducing a Genomic Era in ET

Genomics are starting to play a crucial role in treatment planning for patients with essential thrombocythemia.

When it comes to planning treatment for patients with essential thrombocythemia (ET) — a type of myeloproliferative neoplasm (MPN) — identifying the presence of the JAK2 genetic mutation and understanding its significance can be very important, according to Laura Michaelis, M.D., associate professor of medicine at the Medical College of Wisconsin.

ET is being ushered into the genomic era as treatment protocols are being changed based on a patient’s mutational status. For example, if a patient does not have a JAK2 mutation, he or she is less likely to experience thrombosis and may not need to undergo cytoreductive therapy to control bleeding, regardless of the age at diagnosis. This is an important shift in the treatment paradigm and may prevent patients from having unneeded treatment.

Newsletter

Stay up to date on cancer updates, research and education

Related Videos
Clinical Trial Evaluating Monjuvi in Lymphoma Gives Lasting Responses
Survivors can find strength after cancer by focusing on goals, loved ones, and spiritual connection, especially during challenging or uncertain times.
Image of man with text.
Dr. Breelyn Wilky explains how vague symptoms and testing challenges delay GIST diagnoses
Mark Daniels, an 83-year-old veteran and former fighter pilot, was shocked by his lymphoma diagnosis because he maintained exceptional physical fitness.
Image of man with text.
Image of women, with text.
Image of Dr. with text.
Daniel Jernazian, who beat cancer twice, credits his sports mindset for survival and calls it winning his ‘life World Championship’.
Patients in rural or underserved areas may have worse outcomes, highlighting the need for early support to address care access barriers.
Related Content