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Patritumab Deruxtecan BLA Withdrawn in Non-Small Cell Lung Cancer
The BLA seeking accelerated approval for patritumab deruxtecan in previously treated, locally advanced EGFR-mutated NSCLC in the U.S. has been withdrawn.
FDA Grants Priority Review to Sevabertinib NDA in HER2+ Lung Cancer
The FDA has accepted and granted priority review to an NDA for sevabertinib in previously treated HER2+ non-small cell lung cancer.
Personalizing Prostate Cancer Care With Genetic Testing, PARP Inhibitors
Dr. Kristen Scarpato explains the role of genetic testing in prostate cancer care, as well as its use in determining treatment with PARP inhibitors.
Expanding Access to Screening May Help Prevent Esophageal Cancer
Minimally invasive screening methods offer a more accessible, cost-effective way to detect Barrett’s esophagus early and help prevent esophageal cancer.
HT-KIT Shows Activity in Rare KIT-Driven Cancers, Preclinical Data Finds
Preclinical data has showing compelling findings for HT-KIT among patients with rare and aggressive KIT-driven cancers, including GIST and some leukemias.
Rebuilding Resilience: Navigating Aging and Exercise After CLL
After running the Boston Marathon at 67, I faced new limits from aging and chronic lymphocytic leukemia — but I’ve found ways to stay strong and resilient.
Phase 1/2 Trial Investigating ATR-04 for EGFRi-Related Rashes in Lung Cancer
ATR-04 therapy is being investigated in the phase 1/2 ATR04-484 clinical trial for the treatment of EGFR inhibitor-associated rashes in lung cancer.
Neoadjuvant Efti/Keytruda Combo Improves Tumor Fibrosis Rates in Sarcoma
Neoadjuvant efti and Keytruda plus radiotherapy met the EFTISARC-NEO trial's primary end point by improving tumor fibrosis in soft tissue sarcoma.
Radiation Therapy Eases Symptoms and Improves Targeting in Lung Cancer
Radiation therapy can treat lung cancer at all stages, easing symptoms, improving precision and minimizing side effects with modern techniques.
The Dawn of AI in Prostate Cancer Care
A powerful new ally is emerging in cancer care: artificial intelligence.
Gene Variant May Predict Side Effects From Kidney Cancer Immunotherapy
A variant in the IL-7 gene may predict which patients with kidney cancer are more likely to experience side effects from immunotherapy.
Improving Education and Advocacy in Waldenström Macroglobulinemia
Education and patient advocacy are essential to improving care in Waldenström macroglobulinemia amid clinical advances, according to Dr. Shirley D'Sa.
Connecting With Nature After Colon Cancer: My Self-Care Practices
Connecting with nature through journaling, walking and meditation helped me heal during and after colon cancer treatment.
Dose Escalation Complete in Kidney Cancer Trial of HC-7366 Plus Welireg
A phase 1b study of HC-7366 plus Welireg for advanced clear cell renal cell carcinoma has completed the dose escalation portion of the clinical trial.
First Patient Dosed in MORNINGSTAR Trial of Mavrostobart for Solid Tumors
The first patient has received treatment with mavrostobart plus chemo in the phase 1/2 MORNINGSTAR trial for advanced solid tumors, including lung cancer.
How Essential Thrombocythemia and Polycythemia Vera Affect Blood Flow
Dr. Tiziano Barbui explains how excess blood cell production in certain myeloproliferative neoplasms can impair circulation and why treatments like phlebotomy are used.
What I Would Tell the Woman I Was Before Breast Cancer
After being diagnosed with breast cancer at 39, I learned to advocate for myself, transforming fear into fierce resolve and purpose through every step.
Finding Peace Beyond Caregiving and Oncology
I reflect on my journey from caregiver to advocate, embracing a future shaped by cancer but no longer defined by it.
Understanding Unique Challenges AYA Patients With Cancer Face
Dr. Andrew M. Evens discusses long-term survivorship challenges that can occur among adolescent and young lymphoma survivors.
IDH Inhibitors Offer New, Safer Option for Some Brain Tumors
IDH inhibitors, now FDA approved for lower-grade gliomas, yield fewer side effects than chemotherapy, said Dr. Ryan Merrell.
What I Learned From My Cancer Nurse Maria
Maria, my oncology nurse, inspired lasting change in my life through compassion, wisdom and faith during my cancer surgery and recovery.
Helping the Team While Helping Others
Kathleen Shuey, M.S., RN, SCON, ACNS-BC, listens and guides us in the right direction in caring for our oncology population.
Teaching, Writing, Healing: The Intersections of My Cancer Journey
Fifteen years after being diagnosed with small lymphocytic lymphoma, I’ve found healing and meaning in the work I love and the life I’m grateful to live.
True Grit: The Spirit of an Extraordinary Healer
Heather Patenaude, B.S.N., RN, displays the highest level of technical skills necessary to provide compassionate care to her patients.
Uniting Pediatric and Adult Oncologists to Advance AYA Lymphoma Care
Dr. Andrew M. Evens discusses some of the recent research advancements in AYA lymphoma care that have emerged through clinical trials and initiatives.
Making Something Positive out of Breast Cancer
After my breast cancer treatment, I started a clothing bank to give others free access to recovery items like post-surgery shirts and pillows.
Ovarian Cancer Treatment Side Effects Make for a Difficult Balancing Act
I urge researchers to look into why side effects occur in cancer drugs and to find ways to mitigate them that doesn’t impact their efficacy.
GLP-1 Drugs Linked to Fewer Obesity-Related Cancers
GLP-1 drugs lowered rates of obesity-related cancers and death versus DPP-4s, with no increased cancer risk, study finds.
Breaking Down Treatment Variables in AYA Patients With Cancer
Dr. Andrew M. Evens discussed the importance of differentiating AYA cancers from other age groups, specifically focusing on lymphoma care.
Itovebi Triplet Combo Boosts Survival in HR+, HER2– Breast Cancer
Itovebi plus Ibrance and Faslodex improved overall survival in patients with PIK3CA-mutant, HR+, HER2–, endocrine-resistant breast cancer versus placebo.