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Expanded Access Program May Have Broad Use With Clinical Benefit
March 25th 2019The Food and Drug Administration (FDA) Expanded Access program appeared to have broad use, involved a wide variety of patients and drugs, and derived clinical benefit, according to an initial summary published in JAMA Oncology.
Managing Adverse Events of Breast Cancer with Your Oncology Nurse
March 23rd 2019Debu Tripathy, M.D., the editor in chief of CURE®, recently sat down at the Miami Breast Cancer Conference to discuss the importance of oncology nurses in breast cancer care and offered insight as to how they can keep up-to-date with the constant advancements in the field.
Ovarian Cancer Screening Tool Should be a Top Research Priority
March 21st 2019Did we bring this scary, painful, financially draining monster into our lives by eating too many cookies and not doing enough jumping jacks? We need a reliable diagnostic screening tool for ovarian cancer and we need it now.
Expansion Plans at St. Jude Aim to Help Cure Children in the U.S. and Around the World
March 20th 2019A hospital whose mission is to cure children’s catastrophic diseases is not only providing treatment, but also conducting research and making new medicines. Now, in addition to improving its patient-care and research capabilities, it plans to reach into low-income countries to help cure more children with cancer.
Triplet Combo Yields Durable Responses in Recurrent Epithelial Ovarian Cancer
March 19th 2019Treatment with the combination of Keytruda (pembrolizumab), Avastin (bevacizumab) and metronomic cyclophosphamide appeared safe and effective in women with recurrent epithelial ovarian cancer, according to results from an open-label phase 2 study.
FDA Approves Tecentriq Plus Chemo for Small Cell Lung Cancer
March 19th 2019The Food and Drug Administration (FDA) has granted an approval to the combination of Tecentriq (atezolizumab) with carboplatin and etoposide for the frontline treatment of patients with extensive-stage small cell lung cancer (ES-SCLC).
Initial PARP Inhibitor Use for Ovarian Cancer May Not Lead to Resistance in Secondary Use
March 18th 2019Prior exposure to PARP inhibitor treatment may not lead to resistance in future use with these agents in women with recurrent epithelial ovarian cancer, meaning repeat use could become more common.
Individualized Dosing Regimen Reduces Side Effects in Ovarian Cancer Maintenance Therapy
March 18th 2019Side effects decreased among patients with high-risk ovarian cancer who received an individualized starting dose of Zejula (niraparib), based upon baseline bodyweight and platelet counts, compared with a fixed starting dose.
Zejula Maintenance Therapy Extends Symptom-Free Survival in Recurrent Ovarian Cancer
March 17th 2019Patients with recurrent ovarian cancer who received Zejula (niraparib) maintenance therapy experienced longer progression-free survival, as well as more time without symptoms or toxicity compared with placebo, according to results from the phase 3 ENGOT-OV16/NOVA trial.