Colorectal Cancer | Tumor

CURE’s colorectal cancer page is an extensive resource of cancer information featuring the latest colorectal cancer news, expert oncologist insights on the latest cancer treatments, oncology research, advocacy efforts, and medical data on colorectal cancer.

Immunotherapy Combination ‘Huge Benefit’ for Some Patients With Colorectal Cancer

January 31st 2023

Patients with refractory metastatic colorectal cancer often don’t have many effective treatment options, although immunotherapy may be a promising potential for patients based on recent study findings.

Michael Bublé Discusses His Son’s Cancer, TikTok Star Dies of CRC and More

January 27th 2023

From Michael Bublé opening up about his son’s cancer diagnosis to the death of “Enkyboys” social media star, here’s what’s happening in the oncology space this week.

Adding Avastin to Lonsurf Improved Outcomes in Pretreated Colorectal Cancer

January 25th 2023

Patients with pretreated metastatic colorectal cancer had better outcomes when Avastin was added to their Lonsurf treatment in the third line setting.

Tukysa-Herceptin Approval for Colorectal Cancer Is an ‘Important Breakthrough’ for Chemo-Resistant Disease

January 24th 2023

The FDA recently approved a combination treatment for patients with previously treated metastatic colorectal cancer with HER2-positive disease determined by biomarker testing.

She With Lynch Syndrome

January 23rd 2023

I recently met another woman with Lynch syndrome, the same hereditary cancer syndrome that I have, and it made me reflect on the steps I was taking to maintain my health.

First Patient with Colorectal Cancer Received Nanrilkefusp Alfa in Phase 2 Trial

January 21st 2023

The multicenter study is evaluating the safety and efficacy of nanrilkefusp alfa combined with Erbitux.

FDA Approves Tukysa Plus Herceptin for HER2-Positive Metastatic Colorectal Cancer

January 19th 2023

The FDA approved Tukysa plus Herceptin for previously treated patients with HER2-positive metastatic colorectal cancer.

New KRAS Inhibitor to Be Studied in Lung, Colon and Pancreatic Cancers

January 18th 2023

The COVALENT-102 trial will investigate BMF-219 in patients with non-small cell lung cancer, colorectal and pancreatic cancers.

Blood Test May Determine Which Patients With CRC Need Chemo After Surgery

January 18th 2023

A test that measures tumor DNA in the blood could be a helpful prognostic factor in patients with colorectal cancer who underwent surgery.

Neoadjuvant Therapies and Less Invasive Surgeries May Have Improved Survival for Rectal Cancer Care Over Time

January 10th 2023

Treatments before surgery for rectal adenocarcinoma, a type of rectal cancer, have increased and correlated with preservative surgeries and improved overall survival in the last 16 years, though improvements may still be needed for disease screening, an expert said.

Are You ‘Wasting’ Your Cancer?

January 5th 2023

I’ve heard the phrase, “don’t waste your cancer,” as a way to encourage survivors to tell their stories and donate to nonprofits.

Moderate Exercise May Significantly Impact Outcomes in Colorectal Cancer

December 30th 2022

Exercising moderately every week has been linked to improved disease outcomes at any BMI in patients with colorectal cancer.

Brazilian Soccer Legend, Pelé, Dies of Colon Cancer Complications

December 29th 2022

Pelé died on Dec. 29, 2022, from complications related to his colon cancer.

‘Phantom of the Opera’ Star Dies of Cancer, ‘The Home Edit’ Host Completes Treatment and More

December 9th 2022

From the death of a Broadway actor to TV stars completing treatment, here’s what’s happening in the cancer space this week.

Certain Colorectal Cancer Survivors Should Be Closely Monitored for Lung Metastases

November 1st 2022

Recent research unveiled groups of patients with colorectal cancer who should undergo more frequent scans to detect disease that has spread to the lungs.

Early-Phase Trial to Study Novel Drug, With or Without Keytruda, in Solid Cancers

September 27th 2022

The novel drug PY159 will be studied as a single agent and in combination with Keytruda for patients with certain solid tumors — including ovarian, pancreatic, lung, head and neck, colorectal and breast cancers.

FDA Speeds Up Review of Tukysa Plus Herceptin for Metastatic Colon Cancer

September 20th 2022

The Food and Drug Administration granted a priority review for Tukysa plus Herceptin for patients with pretreated, metastatic colon cancer.

Cancer Taught Me an Unexpected Lesson

September 18th 2022

Despite my mother and grandmother’s history with the disease, I never thought I would one day receive a colon cancer diagnosis.

As I Near the End of My Life With Metastatic Cancer, I’m Writing My Final Chapter

September 15th 2022

As I face the end of my life due to metastatic colorectal cancer, I’m preparing my loved ones for my death — from determining who gets my stuff to writing my eulogy and making my memorial service playlist.

Phase 2 Trial to Study Novel Drug in Pretreated Solid Tumors

September 8th 2022

The first patient was treated in a phase 2 trial assessing the safety and efficacy of navicixizumab, with or without chemotherapy, in colorectal, gastric, ovarian and breast cancer.

Pre-Surgical Chemotherapy May Spare Certain Patients With Rectal Cancer From Major Surgery

August 31st 2022

Patients with early-stage rectal cancer may be able to forego major surgery — thus preserving their organs and quality of life — with a pre-surgical chemotherapy regimen, according to recent study results.

AI May Help Predict Colon Cancer Recurrence

August 30th 2022

Researchers developed an artificial intelligence algorithm to potentially improve the prediction of colon cancer recurrence, which may help patients receive the appropriate treatment.

Trial for At-Home Colorectal Cancer Test Completes Enrollment of More Than 10,000 Patients

August 26th 2022

Many participants enrolled in the CRC-PREVENT trial are from communities often underrepresented in clinical trials due to gender, race and socioeconomic status, among other factors.

New Study to Explore Safety and Efficacy of a Single-Infusion CAR-T Cell Treatment in Patients With Colon Cancer

August 18th 2022

Investigators plan to analyze if treatment with an experimental, CAR-T cell therapy is safe and effective in a small group of patients with relapsed or refractory metastatic colorectal cancer.

Study to Investigate if Exercise Improves Outcomes, Decreases Chemo Side Effects in Colon Cancer

August 16th 2022

A new study will analyze the effect of exercise on chemotherapy tolerability and outcomes in patients with colon cancer.

Investigational Drug-Chemoradiotherapy Combo Improves Treatment Responses in Patients With Advanced Rectal Cancer

August 15th 2022

The researchers hypothesize that treatment with the investigational drug combined with chemoradiotherapy may reduce the need for invasive surgery to remove the rectum and surrounding tissue in this patient population.

Trial Launched to Investigate Novel Triplet Therapy in Treatment of Rare Gastric or Esophageal Cancer

July 13th 2022

The manufacturer of one of the cancer treatments announced that it is also participating in clinical trials assessing the safety and efficacy of their product in colorectal and endometrial cancer.

Tukysa Plus Herceptin May Offer ‘Chemotherapy-Free’ Regimen for HER2-Positive Colon Cancer

July 6th 2022

In a clinical trial, the use of Tukysa plus Herceptin demonstrated promising results in treating patients with HER2-positive metastatic colorectal cancer.

Jemperli Eliminated All Signs of Rectal Cancer in Small Clinical Trial, Warranting Further Research

June 8th 2022

One-hundred percent of patients with stage 2/3 mismatch repair-deficient rectal cancer had their disease disappear after treatment with Jermperli, though more research and longer follow-up is needed.

A Couple’s Cancer Journey Reversed in the Blink of an Eye

June 7th 2022

Actress and comedian Jessica St. Clair and her husband, Dan O’Brien, share their roles of partner and parent, but also patient and cancer caregiver, as their roles were reversed in the blink of an eye.