Colorectal Cancer | Tumor

CURE’s colorectal cancer page is an extensive resource of cancer information featuring the latest colorectal cancer news, expert oncologist insights on the latest cancer treatments, oncology research, advocacy efforts, and medical data on colorectal cancer.

Early-Phase Trial to Study Novel Drug, With or Without Keytruda, in Solid Cancers

September 27th 2022

The novel drug PY159 will be studied as a single agent and in combination with Keytruda for patients with certain solid tumors — including ovarian, pancreatic, lung, head and neck, colorectal and breast cancers.

FDA Speeds Up Review of Tukysa Plus Herceptin for Metastatic Colon Cancer

September 20th 2022

The Food and Drug Administration granted a priority review for Tukysa plus Herceptin for patients with pretreated, metastatic colon cancer.

Cancer Taught Me an Unexpected Lesson

September 18th 2022

Despite my mother and grandmother’s history with the disease, I never thought I would one day receive a colon cancer diagnosis.

As I Near the End of My Life With Metastatic Cancer, I’m Writing My Final Chapter

September 15th 2022

As I face the end of my life due to metastatic colorectal cancer, I’m preparing my loved ones for my death — from determining who gets my stuff to writing my eulogy and making my memorial service playlist.

Phase 2 Trial to Study Novel Drug in Pretreated Solid Tumors

September 8th 2022

The first patient was treated in a phase 2 trial assessing the safety and efficacy of navicixizumab, with or without chemotherapy, in colorectal, gastric, ovarian and breast cancer.

Pre-Surgical Chemotherapy May Spare Certain Patients With Rectal Cancer From Major Surgery

August 31st 2022

Patients with early-stage rectal cancer may be able to forego major surgery — thus preserving their organs and quality of life — with a pre-surgical chemotherapy regimen, according to recent study results.

AI May Help Predict Colon Cancer Recurrence

August 30th 2022

Researchers developed an artificial intelligence algorithm to potentially improve the prediction of colon cancer recurrence, which may help patients receive the appropriate treatment.

Trial for At-Home Colorectal Cancer Test Completes Enrollment of More Than 10,000 Patients

August 26th 2022

Many participants enrolled in the CRC-PREVENT trial are from communities often underrepresented in clinical trials due to gender, race and socioeconomic status, among other factors.

New Study to Explore Safety and Efficacy of a Single-Infusion CAR-T Cell Treatment in Patients With Colon Cancer

August 18th 2022

Investigators plan to analyze if treatment with an experimental, CAR-T cell therapy is safe and effective in a small group of patients with relapsed or refractory metastatic colorectal cancer.

Study to Investigate if Exercise Improves Outcomes, Decreases Chemo Side Effects in Colon Cancer

August 16th 2022

A new study will analyze the effect of exercise on chemotherapy tolerability and outcomes in patients with colon cancer.

Investigational Drug-Chemoradiotherapy Combo Improves Treatment Responses in Patients With Advanced Rectal Cancer

August 15th 2022

The researchers hypothesize that treatment with the investigational drug combined with chemoradiotherapy may reduce the need for invasive surgery to remove the rectum and surrounding tissue in this patient population.

Trial Launched to Investigate Novel Triplet Therapy in Treatment of Rare Gastric or Esophageal Cancer

July 13th 2022

The manufacturer of one of the cancer treatments announced that it is also participating in clinical trials assessing the safety and efficacy of their product in colorectal and endometrial cancer.

Tukysa Plus Herceptin May Offer ‘Chemotherapy-Free’ Regimen for HER2-Positive Colon Cancer

July 6th 2022

In a clinical trial, the use of Tukysa plus Herceptin demonstrated promising results in treating patients with HER2-positive metastatic colorectal cancer.

Jemperli Eliminated All Signs of Rectal Cancer in Small Clinical Trial, Warranting Further Research

June 8th 2022

One-hundred percent of patients with stage 2/3 mismatch repair-deficient rectal cancer had their disease disappear after treatment with Jermperli, though more research and longer follow-up is needed.

A Couple’s Cancer Journey Reversed in the Blink of an Eye

June 7th 2022

Actress and comedian Jessica St. Clair and her husband, Dan O’Brien, share their roles of partner and parent, but also patient and cancer caregiver, as their roles were reversed in the blink of an eye.

How Naming My Lifesaving Ostomy Helped Me Gain Confidence and Find Body Positivity

May 19th 2022

After being diagnosed with colorectal cancer, my ostomy — which I named Toodles — opened up a world of body positivity for me.

If I Can Save One Life By Telling My Cancer Story, It Was All Worth It

May 18th 2022

After being diagnosed with stage 4 colorectal cancer, I made it a mission to share my story and help others.

Extraordinary Oncology Nurse, Extraordinary Person

May 7th 2022

Donna MacDonald, B.S.N., RN, OCN, CCM, goes beyond her duties as a nurse to advocate and support her patients.

Use of Live-Donor Liver Transplants in Patients With Metastatic Colon Cancer Leads to ‘Excellent Survival’

March 31st 2022

Patients with colorectal cancer that has spread to the liver tend to have poor outcomes and are typically not candidates to receive liver transplants from deceased donors. However, results from a small study on transplanting livers from live-donors could "change this paradigm," an expert said.

Healthy Diet and Lifestyle May Improve Survival Rates for Patients With Stage 3 Colon Cancer

January 31st 2022

Patients with stage 3 colon cancer should feel empowered to start a healthy lifestyle and diet, says a researcher, after recent study results demonstrated positive survival and recurrence outcomes.

My Dad’s Death From Cancer Forced Me Out of the Shadows and Into a Spotlight of Advocacy

January 31st 2022

A teenager from Pennsylvania whose father died from colorectal cancer explains the impact it had on her life and how she has stepped into the field of advocacy to help others.

‘Let’s Go After This Thing and Fight’ Urges a Long-Time Survivor of Early-Onset CRC

January 27th 2022

In this episode of the “Cancer Horizons” podcast, a woman living with colorectal cancer who was diagnosed 14 years ago at age 29 discusses what it was like to be the youngest person in the treatment room, and how she found another community of young survivors.

Keytruda Plus Mektovi and Avastin Associated With Survival Benefit in Metastatic Colon Cancer

January 25th 2022

A group of patients with microsatellite-stable, treatment-refractory metastatic colorectal cancer experienced responses to treatment with Keytruda plus Mektovi and Avastin.

Blood Test Results May Identify Which Patients With CRC May Benefit From Post-Surgical Chemotherapy

January 25th 2022

The use of a ctDNA assay could help determine which patients with colorectal cancer may benefit most from chemotherapy after surgery.

First-In-Human Clinical Trial of Investigational Therapy for Multiple Advanced Solid Tumors Is Underway

January 21st 2022

Researchers plan to enroll 60 patients in the first-in-human phase 1 clinical trial to assess the safety and preliminary clinical activity of an anti-CD39 monoclonal antibody to treat advanced solid tumors.

Enrollment Begins for First-Line Maintenance Vaccine for Metastatic CRC

January 13th 2022

Enrollment has begun for a trial evaluating a vaccine as first-line maintenance treatment for metastatic, microsatellite-stable colorectal cancer.

‘Shock to the Heart’: A Cancer Survivor Recalls the Emotions of Her First Chemo Treatment

January 12th 2022

After not knowing quite what to expect from her first chemotherapy treatment, colorectal cancer survivor Yla Flores describes the pain she felt in her heart after seeing other patients in worse conditions.

Former MLB Pitcher Jim Corsi Dies After Cancer, Actress Brittany Daniel Uses Twin as Surrogate and More

January 7th 2022

From former Boston Red Sox pitcher Jim Corsi’s death after cancer to how “Sweet Valley High” actress Brittany Daniel’s unique experience after cancer caused pregnancy difficulties, here’s what’s happening in the cancer landscape this week.

Although Physicians Prefer Colonoscopy, Many Are Implementing Shared Decision-Making With Patients in Colon Cancer Screening

January 6th 2022

“It is frequently said that the best screening test is the one patients are willing to complete,” a researcher said. However, some experts note that colonoscopies are the gold standard for detecting and confirming colorectal cancer.

Genomic Features in Young Adults With Cancer May Differ Than in Older Patients, Which May Help Steer Treatment Decisions

December 27th 2021

As cancer incidence increases in young adults, understanding the genomic profiles of tumors in young adults may guide treatment options such as immunotherapy.