Colorectal Cancer

Investigators plan to analyze if treatment with an experimental, CAR-T cell therapy is safe and effective in a small group of patients with relapsed or refractory metastatic colorectal cancer.

A new study will analyze the effect of exercise on chemotherapy tolerability and outcomes in patients with colon cancer.

The researchers hypothesize that treatment with the investigational drug combined with chemoradiotherapy may reduce the need for invasive surgery to remove the rectum and surrounding tissue in this patient population.

The manufacturer of one of the cancer treatments announced that it is also participating in clinical trials assessing the safety and efficacy of their product in colorectal and endometrial cancer.

In a clinical trial, the use of Tukysa plus Herceptin demonstrated promising results in treating patients with HER2-positive metastatic colorectal cancer.

One-hundred percent of patients with stage 2/3 mismatch repair-deficient rectal cancer had their disease disappear after treatment with Jermperli, though more research and longer follow-up is needed.

Actress and comedian Jessica St. Clair and her husband, Dan O’Brien, share their roles of partner and parent, but also patient and cancer caregiver, as their roles were reversed in the blink of an eye.

After being diagnosed with colorectal cancer, my ostomy — which I named Toodles — opened up a world of body positivity for me.

After being diagnosed with stage 4 colorectal cancer, I made it a mission to share my story and help others.

Donna MacDonald, B.S.N., RN, OCN, CCM, goes beyond her duties as a nurse to advocate and support her patients.

Patients with colorectal cancer that has spread to the liver tend to have poor outcomes and are typically not candidates to receive liver transplants from deceased donors. However, results from a small study on transplanting livers from live-donors could "change this paradigm," an expert said.

Patients with stage 3 colon cancer should feel empowered to start a healthy lifestyle and diet, says a researcher, after recent study results demonstrated positive survival and recurrence outcomes.

A teenager from Pennsylvania whose father died from colorectal cancer explains the impact it had on her life and how she has stepped into the field of advocacy to help others.

A group of patients with microsatellite-stable, treatment-refractory metastatic colorectal cancer experienced responses to treatment with Keytruda plus Mektovi and Avastin.

The use of a ctDNA assay could help determine which patients with colorectal cancer may benefit most from chemotherapy after surgery.

Researchers plan to enroll 60 patients in the first-in-human phase 1 clinical trial to assess the safety and preliminary clinical activity of an anti-CD39 monoclonal antibody to treat advanced solid tumors.

Enrollment has begun for a trial evaluating a vaccine as first-line maintenance treatment for metastatic, microsatellite-stable colorectal cancer.

From former Boston Red Sox pitcher Jim Corsi’s death after cancer to how “Sweet Valley High” actress Brittany Daniel’s unique experience after cancer caused pregnancy difficulties, here’s what’s happening in the cancer landscape this week.

“It is frequently said that the best screening test is the one patients are willing to complete,” a researcher said. However, some experts note that colonoscopies are the gold standard for detecting and confirming colorectal cancer.

As cancer incidence increases in young adults, understanding the genomic profiles of tumors in young adults may guide treatment options such as immunotherapy.

From the death of Nick Cannon’s five-month-old son due to brain cancer to the late-stage diagnosis of Kansas City reporter Matt Stewart’s wife, here’s what’s happening in the cancer landscape this week.

The incidence of young-onset colorectal cancer has been increasing in the past years, and despite being more physically active and receiving more intense treatments, younger patients are not living longer with the disease than older patients.

From the death of Frederik Willem de Klerk to study results showing palm oil contains an acid that may cause cancer spread, here’s what’s happening in the cancer landscape this week.

A woman with Lynch syndrome discusses testing young people for hereditary cancer syndromes and emphasizes the importance of speaking with a genetic counselor.

The first patients were dosed in a phase 2 trial for a topical gel to treat lesions in patients with colorectal cancer receiving EGFR inhibitor therapy.

Treatments for bladder, colorectal and prostate cancer may cause sexual dysfunction in men. Here, an expert provides insight into how patients and survivors may improve their sexual health.

The FDA has approved Braftovi plus Erbitux for pretreated patients with BRAF V600E-mutant metastatic colorectal cancer.

A woman explains how her Lynch syndrome diagnosis altered the way she lives her life, and shares advice for others on how to shift their priorities while maintaining positivity and hope.

The prescription of systemic cancer therapies varies based on a patient’s age, comorbidities, cancer stage and other variables, according to recent research.

The eligible age of 65 years for Medicare may be discouraging patients from getting screenings and tests as they wait for more health coverage.