New Drug Combination May Improve Outcomes in Unresectable Liver Cancer

January 27th 2022

Brielle Benyon

An expert from Memorial Sloan Kettering Cancer Center in New York discusses the promising findings from a study that analyzed tremelimumab plus Imfinzi for unresectable hepatocellular carcinoma, and outlines side effects patients should discuss with their doctor.

Combination Therapy for Advanced Kidney Cancer Subtype May Lead Patients to Live Longer, Better Lives

January 27th 2022

Darlene Dobkowski, MA

Opdivo plus Cabometyx prolonged survival with minimal effects to their health status, which may highlight the need for patients to advocate for their quality of life when making treatment decisions.

Knowledge Is Power: How NBC’s ‘The More You Know’ Influenced My Cancer Experience

January 27th 2022

Bonnie Annis

A breast cancer survivor discusses how researching cancer risks and environmental factors made her feel better equipped with information against the disease.

‘Let’s Go After This Thing and Fight’ Urges a Long-Time Survivor of Early-Onset CRC

January 27th 2022

Jamie Cesanek

In this episode of the “Cancer Horizons” podcast, a woman living with colorectal cancer who was diagnosed 14 years ago at age 29 discusses what it was like to be the youngest person in the treatment room, and how she found another community of young survivors.

First Allogeneic RNA Cell Therapy Clinical Trial Begins in Multiple Myeloma

January 27th 2022

Jamie Cesanek

A clinical trial to evaluate Descartes-25, a novel allogeneic RNA cell therapy, for multiple myeloma has officially treated its first patient and is now recruiting in certain locations.

Adagrasib Confers High Response Rates in Several Gastrointestinal, Pancreatic Tumors

January 26th 2022

Audrey Sternberg

Single-agent adagrasib was associated with encouraging treatment responses in patients with previously treated non-colorectal gastrointestinal tumors and pancreatic ductal adenocarcinoma.

Oral Antimetabolite After Surgery Associated With Survival Benefit in Biliary Tract Cancer

January 26th 2022

Ariana Pelosci

Patients with biliary tract cancer achieved a better survival outcome after receiving treatment with an oral antimetabolite following surgical resection than patients who only were treated with surgery.

My Experience Enrolling in a Cancer Clinical Trial: The Verdict Is ‘Yes’

January 26th 2022

Julie S. Brokaw

A patient with ovarian cancer describes how she enrolled in a clinical trial, and how it has given her a renewed sense of hope that she may find a successful treatment option.

‘Life Is Never the Same Again’: Cancer Survivors Describe the Most Difficult Elements of Survivorship

January 26th 2022

Jamie Cesanek

From mental impacts such as “scanxiety” and post-traumatic stress disorder to difficulties returning to work/dating and long-term physical side effects like memory issues, several cancer survivors shared the hardest part about survivorship.

FDA Approves Kimmtrak for Unresectable or Metastatic Uveal Melanoma

January 26th 2022

Darlene Dobkowski, MA

Kimmtrak is the first-ever drug to be granted FDA approval for this patient population of HLA-A*02:01-positive metastatic or unresectable uveal melanoma.

Cosibelimab Elicits Positive Tumor Response in Patients With Metastatic Skin Cancer Subtype

January 25th 2022

Jamie Cesanek

Patients with metastatic cutaneous squamous cell carcinoma achieved promising response rates after treatment with cosibelimab. If approved, drug developers are hoping to offer cosibelimab as a more affordable immunotherapy option for this patient population.

For Better and for Worse: How the COVID-19 Pandemic Changed Cancer Care

January 25th 2022

Brielle Benyon

The COVID-19 pandemic drastically impacted many facets of cancer care. Although some changes were detrimental, an expert from Johns Hopkins Medicine notes others actually improved accessibility to care.

‘Let’s Take the Stairs:’ How I Encouraged My Daughter to Get Exercise During Cancer Treatments

January 25th 2022

Debbie Legault

A mother of a breast cancer survivor explains how she and her daughter creatively incorporated exercise into her daughter’s daily routine to improve her physical and mental health during treatment.

Keytruda Plus Mektovi and Avastin Associated With Survival Benefit in Metastatic Colon Cancer

January 25th 2022

Ryan McDonald

A group of patients with microsatellite-stable, treatment-refractory metastatic colorectal cancer experienced responses to treatment with Keytruda plus Mektovi and Avastin.

Blood Test Results May Identify Which Patients With CRC May Benefit From Post-Surgical Chemotherapy

January 25th 2022

Ariana Pelosci

The use of a ctDNA assay could help determine which patients with colorectal cancer may benefit most from chemotherapy after surgery.

VHL-Related Kidney Cancer Survivor Reflects on Decades of Change for the Rare Condition

January 24th 2022

Brielle Benyon

When Joseph Heisler was diagnosed with von Hippel-Lindau disease 30 years ago, there was hardly any information on the condition. Fast forward three decades, there is an FDA-approved drug and a handbook of information available in two languages.

Kymriah Shows ‘Huge Potential’ for Patients With Heavily Pretreated, Relapsed Follicular Lymphoma

January 24th 2022

Colleen Moretti

Kymriah may represent a more effective option than currently available treatments for patients with heavily pretreated follicular lymphoma, according to an expert from The University of Texas MD Anderson Cancer Center.

Support From Beyond: How My Deceased Loved Ones Helped Me Navigate My Cancer Journey

January 24th 2022

Jessica Bolz

A survivor of multiple cancers explains how “visits” from deceased friends and loved ones made her feel safe before undergoing treatments.

Gut Microbiome Makeup May Help Predict Skin-Related Immunotherapy Side Effects in Patients With Gastric Cancer

January 24th 2022

Lindsay Fischer

Patients with gastric cancer who present with certain bacteria in their gut were found to be more likely to experience skin-related side effects from Opdivo treatment, research showed.

Early Non-Small Cell Lung Cancer: The IMpower010 Trial

January 24th 2022

Jessica Donington, MD, MSCR

An expert oncologist details the design, outcomes, and clinical implications of the IMpower010 trial.

Early Non-Small Cell Lung Cancer and the ADAURA Trial

January 24th 2022

Jessica Donington, MD, MSCR

Dr. Jessica Donington explains how the results of the ADAURA trial changed the treatment algorithm in the adjuvant setting in early non-small cell lung cancer.

Patients With Unresectable Liver Cancer May Have a ‘Promising and Tolerable’ Treatment Option With Combination Therapy

January 24th 2022

Colleen Moretti

The use of a non-invasive procedure combined with Lenvima plus Tyvyt demonstrated safe and effective results in patients with liver cancer not eligible for surgical resection.

Will Genetic Testing Help People With Metastatic Cancer?

January 24th 2022

The bottom line seems to be yes, genetic testing for inherited mutations may help tailor treatment for all with advanced or metastatic cancer.

Here’s to Appreciating Life and the Places You’ll Go, Despite Living With Cancer

January 23rd 2022

Marissa Holzer

A woman living with metastatic breast cancer describes how the death of a friend’s grandmother reminded her of her own grandmother’s passing and the lessons she learned about life from it that she applies in her cancer journey.

Lenvima May Offer Survival Benefit With Manageable Side Effects in Recurrent HCC After Liver Transplantation

January 23rd 2022

Darlene Dobkowski, MA

Researchers observed this benefit in recurrent HCC after liver transplantation, which represents a patient population often excluded from clinical trials due to potential organ rejection.

Major Developments in Kidney Cancer in 2021

January 23rd 2022

2021 was a bumper year for kidney cancer developments, including several new treatment approvals by the FDA and a much better understanding of how kidney cancer is impacted by COVID-19 infections and vaccines.

As I Begin Another Year of Cancer Treatment, I Struggle Over Why I’m Still Here and Others Aren’t

January 22nd 2022

Kelly Irvin

A patient with stage 4 ovarian cancer still receiving treatment six years after her first diagnosis explains that even though she’s exhausted from all her treatments and the related side effects, she knows many others don’t survive as long as she has.

Frontline Lenvima Provided Survival Benefit for Patients With Liver Cancer

January 22nd 2022

Jamie Cesanek

Treating patients with liver cancer initially with Lenvima instead of the standard of care was associated with a survival benefit, according to recent research.

Minimally Invasive Procedure Combined with Lenvima and Checkpoint Blockade Shows Promise in Unresectable Liver Cancer

January 21st 2022

Brielle Benyon

The use of a minimally invasive procedure — known as trans-arterial chemoembolization — plus Lenvima and a PD-1 checkpoint blockade drug proved to be safe and efficacious in patients with unresectable advanced liver cancer.

‘Make an Impact and Seize the Day’ Says Cancer Survivor Who Launched Kindness Challenge

January 21st 2022

Brielle Benyon

Lorelei Colbert was diagnosed with triple-negative breast cancer at 28 and used her experience to launch the “Chemo to Kindness” challenge that inspired others around the world to do acts of good.