Patient Education, Shared Decision-Making, and Optimizing Care for ESR1-Mutated Breast Cancer

Clinical Brief: Implementation and Patient Support Strategies

Main Discussion Topics:

• Role of multidisciplinary care team in patient education and support
• Importance of early intervention for side effect management
• Strategies for ensuring medication adherence with oral therapy
• Value of nurse coordinators and pharmacist integration
• Flexible approaches, including chemotherapy-endocrine therapy sequencing

Key Points for Physicians:

• Team-based approach crucial for successful oral therapy management
• Early touchpoints in first month prevent long-term discontinuation
• Patient education impacts adherence and anxiety management
• Consider short-course chemotherapy followed by endocrine therapy in select cases
• Communication protocols essential for optimal outcomes

The discussion highlighted that successful implementation of oral targeted therapies requires comprehensive support systems and proactive communication strategies to ensure optimal patient outcomes and treatment adherence.