One Million Strong
January 25, 2018 – Kristie L. Kahl
A Cut Above Open Surgery
March 17, 2018 – MEERI KIM, PH.D.
High Expectations for Immunotherapy in GI Cancers
March 18, 2018 – ARLENE WEINTRAUB
Cabometyx Improves Survival in Patients With Advanced Hepatocellular Carcinoma
March 21, 2018 – Silas Inman
Immunotherapy After Targeted Drug Shows Promise in Advanced Liver Cancer
March 22, 2018 – Wayne Kuznar
On the Double: Improving Survival Rates in Pancreatic Cancer
March 25, 2018 – JANE DE LARTIGUE, PH.D.
Chemo Regimen Helps Control Locally Advanced Pancreatic Cancer
March 23, 2018 – Silas Inman
Beneath the Surface: Advancing Treatment for Cholangiocarcinoma
March 31, 2018 – Beth Fand Incollingo
Paying it Forward
March 30, 2018 – Beth Fand Incollingo
All Over the Map When It Comes to Survivorship
April 04, 2018 – BETH FAND INCOLLINGO and STACY VERNER
A Major Turnaround for Liver Cancer
April 04, 2018 – GINA COLUMBUS and BETH FAND INCOLLINGO
Currently Viewing
A New Year Brings Treatment Options and Hope for Patients With Gastrointestinal Cancers
April 05, 2018 – MIKE HENNESSY, SR.
Looking Within: Exploring Genomic Testing for GI Cancers
April 05, 2018 – Danielle Bucco

A New Year Brings Treatment Options and Hope for Patients With Gastrointestinal Cancers

It's amazing what a new year can bring.
BY MIKE HENNESSY, SR.
PUBLISHED April 05, 2018
IT’S AMAZING WHAT A new year can bring.

At this time last year, patients with hepatocellular carcinoma were facing the fact that no new treatments for their disease had been approved in about 10 years.

Now, after initial therapy, these patients have the opportunity to consider two recently approved treatments: the targeted drug Stivarga (regorafenib) and the immunotherapy Opdivo (nivolumab). Meanwhile, according to recent clinical trial results, an additional targeted drug and another immunotherapy also look promising.

These are extremely exciting developments in a field that, over the last decade, has been marked by much effort — and just as much frustration.

The story is similar in a rare subtype of liver cancer, cholangiocarcinoma, which affects the bile ducts.

At the annual conference of the Cholangiocarcinoma Foundation in February 2017, experts didn’t have much to offer when it came to emerging treatments for the condition. But this winter, the conference was brimming with news demonstrating a growing understanding of the genomics of the disease — a major step toward finding new therapies.

Scientists have not only identified a long list of genetic mutations that can drive cholangiocarcinomas, but have begun to classify these cancers into subtypes with different treatment needs. And they likely won’t have to start from scratch when it comes to developing those treatments: There are a number of existing targeted therapies that may be effective.

These are just some of the reasons we’re excited to present you with this special issue on gastrointestinal (GI) cancers, which also delves into the use of immunotherapy in GI cases characterized as microsatellite instability-high (MSI-high), meaning that cancer cells have trouble repairing their own DNA when it’s damaged.

Rounding out the issue are summaries of new research into treatments for pancreatic and anal cancers, and a consideration of the most cost-effective surgical methods for colorectal cancer. We hope that this array of information will leave you with a positive outlook about the ever-improving state of treatment for GI cancers. More specifically, our aim is to provide you with information that will help you make informed, confident decisions about your own course of treatment.

As always, thank you for reading.

MIKE HENNESSY, SR.
Chairman and CEO
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