April 14th 2025
AU-007, combined with Opdivo and low-dose aldesleukin, has entered a phase 2 melanoma trial, with early data showing activity and manageable safety.
April 12th 2025
KSQ-004EX is being evaluated in solid tumors including melanoma, non-small cell lung, head and neck, colorectal, pancreatic and cervical cancer.
April 11th 2025
CURE spoke with Dr. Michael K. Wong and Dr. Diwakar Davar about the use of ctDNA for patients with melanoma, and where the field may be headed.
April 10th 2025
I was diagnosed with stage 3 melanoma at 31, faced recurrence and now share my journey to raise awareness, stay hopeful and trust in God’s plan.
April 4th 2025
The FDA granted Breakthrough Therapy designation to IDE196 for the neoadjuvant treatment of primary uveal melanoma when enucleation has been recommended.
First Patient Dosed in Trial of [212Pb]VMT01 for Metastatic Melanoma
The first patient has been dosed with [212Pb]VMT01 in a phase 1/2a trial evaluating the safety of the agent in patients with melanoma.
Solnerstotug Demonstrates Early Efficacy in PD-L1 Resistant Tumors
Favorable initial results from a phase 1/2 trial of solnerstotug in PD-L1–resistant tumors showed a 14% response rate and 62% disease control rate.
How Subcutaneous vs IV May Affect Treatment Adherence in Cancer Care
Dr. Eric K. Singhi shares his insights into the advantages of the subcutaneous formulation of Opdivo versus the IV version for patients with solid tumors.
The FDA Accepts a BLA for RP1 Plus Opdivo in Advanced Melanoma
The FDA has accepted a BLA for treatment with RP1 in combination with Opdivo for patients with advanced melanoma who have progressed on prior therapy.
The Significance of the Subcutaneous Opdivo FDA Approval in Solid Tumors
Dr. Balazs Halmos discusses the significance of the approval of subcutaneous Opdivo and what this treatment formulation means for those with solid tumors.
The Subcutaneous Approval of Opdivo Makes Waves in Future of Cancer Care
Subcutaneous Opdivo improves cancer care by offering faster, accessible therapy, reducing time toxicity and expanding patient access, according to experts.
Understanding the Benefit of Subcutaneous Versus IV Opdivo in Patients With Solid Tumors
Dr. Eric K. Singhi discusses the benefit of subcutaneous immunotherapy following the FDA approval of subcutaneous Opdivo for patients with solid tumors.
Top 5 Cancer Vaccine Stories from 2024
With breakthroughs from melanoma to pancreatic cancer, this has been a year of great promise in the field of cancer vaccines.
NFL Star Randy Moss Undergoing Cancer Treatment, Montell Jordan Shares Update and More
From a Pro Football Hall of Famer announcing his diagnosis to an R&B star’s latest update, here’s what’s happening in the cancer space this week.
First Patient Enrolled Receives Kimmtrak in Phase 3 Uveal Melanoma Trial
The first patient was enrolled in a phase 3 trial for patients with non-metastatic uveal melanoma to either receive Kimmtrak or observation.
Nemvaleukin Shows Manageable Safety Profile in Advanced Solid Tumors
In patients with advanced solid tumors, treatment with nemvaleukin with or without Keytruda demonstrated antitumor activity and tolerability.
Opdivo and Yervoy May Improve Survival for Resected Stage 3/4 Melanoma
Patients with resected stage 3 or 4 melanoma treated with immune-oncology agents demonstrated significantly higher cure rates compared to those treated with placebo.
Longer Time Until Recurrence Associated With Better Melanoma Outcomes
An expert explains study findings that associate a longer time until postsurgical melanoma recurrence with improved progression and survival.
Long-Term Study Data Support Keytruda as Standard of Care for Advanced Melanoma
Keytruda continued to improve survival versus Yervoy in unresectable stage 3 or 4 melanoma in long-term follow-up data.
Oncology Drugs Approved by the FDA in September 2024
Throughout September, the FDA approved drugs for the treatment of diseases including lung cancer, multiple myeloma, thyroid cancer and breast cancer.
Survival Benefit Continues at 10 Years From Opdivo Either Alone or With Yervoy in Advanced Melanoma
Findings from the CheckMate 067 of patients with advanced melanoma include the longest follow-up of a checkpoint inhibitor in any tumor type.
FDA to Speed Up Review of IBI363 for Advanced Melanoma
The Food and Drug Administration granted a fast track designation to IBI363 for patients with unresectable advanced or metastatic melanoma.
Immunotherapy Combination Elicit Waves of Response in Advanced Melanoma
A new algorithm has found that combining immune checkpoint inhibitors bolsters immune response among some patients with advanced melanoma.
Cancer Vaccine for NSCLC and Melanoma Could Be Paradigm-Changing
The cancer vaccine, mRNA-4157, garnered immune responses of 30 weeks among some patients with melanoma and lung cancer, study results showed.
Questions Patients Should Ask After a Cancer Diagnosis
We asked oncology experts what questions patients should ask their doctors soon after receiving a cancer diagnosis. This is their advice.
Presurgical Targeted Therapy, Immunotherapy Show Responses in Melanoma
Researchers have found that among patients with certain melanoma, presurgical targeted therapy and immunotherapy can result in better pathologic response.
Researchers Urge Caution of Immunotherapy in Older Patients with Melanoma
Citing toxicities and lack of efficacy, some are calling for caution when treating older patients with melanoma with immune checkpoint inhibitors.
OBX-115 Receives FDA Fast Track Designation in Advanced Melanoma
The TIL therapy OBX-115 ‘may have the potential to address’ an unmet need among patients with metastatic or locally advanced melanoma.
Presurgical, Postsurgical Targeted Therapy Effective in Some Melanomas
Perioperative treatment with BRAF and MEK inhibitors was found to benefit some patients with stage 3 and 4 melanoma, according to a recent study.
New Cancer Vaccine Shows Promise in Melanoma
Following promising European trial results, a new peptide vaccine for melanoma is being studied in America, with results expected next year.
Shifting the Spotlight to Cancer Vaccines
With many groundbreaking cancer therapies on the horizon, it's also time to focus on up and coming cancer vaccines.
Cancer Vaccines Are a 'Marvel'
Are cancer vaccines the new frontier in oncology? Experts and patients weigh in from the front lines.
A Poem About Finding Purpose and Looking Ahead During Cancer
Learning that I had cancer — melanoma and renal cell carcinoma — made me feel like I lost something, but I keep looking ahead.
Long-Term Follow-Up Still Shows Tafinlar/Mekinist Benefit in Melanoma
Eight-year follow-up showed that Tafinlar plus Mekinist continued to improve outcomes for patients with stage 3 melanoma.
FDA to Review Injectable Opdivo for All Approved Indications
The Food and Drug Administration granted a Biologics License Application for subcutaneous Opdivo for potential approval.