Bladder Cancer | Tumor

CURE’s bladder cancer page is a go-to resource for oncology news and updates in the world of bladder cancer. Here, readers will find cancer articles, videos, podcasts, and more with expert insight into the latest treatments and research in bladder cancer.

Immunotherapy in GU Cancers: Combinations Are the Next Step

May 4th 2018

Immunotherapy is making landmark change in the treatment of patients with genitourinary (GU) cancers, with bladder cancer being the pioneer in the field, having five FDA-approved checkpoint inhibitors. But kidney cancer is not far behind, with a breakthrough therapy designation granted for a Keytruda (pembrolizumab) combination this past January.

Combination Improves Responses, Misses Survival Endpoint in Bladder Cancer Trial

April 25th 2018

The combination use of Cyramza (ramucirumab) plus docetaxel showed improvements in objective response rate (ORR) and a positive trend in overall survival (OS) among patients with advanced bladder cancer, according to additional results from the phase 3 RANGE trial.

Concurrent Chemo, Immunotherapy Offers Viable Option in Metastatic Bladder Cancer

April 21st 2018

In particular, patients whose tumors have certain genetic mutations may respond especially well to this combination approach.

There Are Multiple Dynamic Biomarkers for Bladder Cancer

April 20th 2018

While there are a few common and well-known checkpoints for bladder cancer, there are also many more than PD-1, PD-L1 and CTLA-4.

Chemotherapy Could Make a Comeback, But Only Clinical Trials Will Tell

March 23rd 2018

Chemotherapy can aid in making a tumor “hot” – meaning that it attracts tumor-infiltrating lymphocytes (TILs), which are linked to killing tumor cells – priming it to respond better to immunotherapy treatment.

Patient Education Key in Flexible Dosing Schedule for Opdivo

March 22nd 2018

After a recent FDA approval for an additional dosing schedule option for Opdivo, patients must be educated on the potential side effects that may occur between prolonged visits.

Patients Now Have the Option to Undergo Immunotherapy Less Frequently

March 6th 2018

The Food and Drug Administration (FDA) has approved a supplemental biologics license application adding a four-week dosing schedule for Opdivo (nivolumab) across several of the PD-1 inhibitor’s indications.

Efficacy Offsets High Costs for Immunotherapy in US, But Not Overseas

February 14th 2018

Researchers from Israel, the United Kingdom (UK) and Canada sought to determine the cost-effectiveness of Keytruda for the second-line treatment of patients with advanced bladder cancer. Drug costs were compared between the US, UK, Canada and Australia.

Dietary Intervention Helps Pre-Diabetic Patients With Bladder Cancer

February 10th 2018

Patients with diabetes are at a greater risk for bladder cancer, and worse, for disease recurrence and progression. So, recent research investigated if a certain diet would help.

Managing Toxicity Amidst Immunotherapy Expansion in Bladder Cancer Is Critical

February 5th 2018

Now that a number of immunotherapy agents have been approved in the bladder cancer space, identifying and managing the toxicities that may come along with them is critical.

The Future of Bladder Cancer Treatment

January 25th 2018

Daniel J. George, M.D., discusses the role of immunotherapy, its continued integration into standards of care and what else the future holds for the treatment of bladder cancer.

Inner-Ear Buildup of Cisplatin May Cause Hearing Loss

January 5th 2018

“As the population of cancer survivors continues to grow, so does the importance of addressing the long-term sequelae of cancer treatment,” the authors wrote. “This hearing loss can result in multifaceted decrease in quality of life, and in pediatric patients it can impact social and academic development.”

Combination Immunotherapy Shows Promise for Bladder Cancer

December 26th 2017

When combined with other regimens in the treatment of patients with bladder cancer, immunotherapy has been shown to be beneficial, according to Arjun Balar, M.D.

Immunotherapy Combinations Are Being Explored in Bladder Cancer

December 13th 2017

To take the next step in this research, investigators are now combining immunotherapies together, or with chemotherapy, to create added benefits and more durable, long-lasting responses.

2017 Was the Year of Immunotherapy for Bladder Cancer

December 13th 2017

There were monumental advances in the treatment of bladder cancer during the year 2017, with five approvals for checkpoint inhibitors in both the first and second line setting

Upfront Chemotherapy Improves Survival in Bladder Cancer Subtype

December 12th 2017

When given neoadjuvant chemotherapy before getting a radical cystectomy, patients with the basal subtype of muscle-invasive bladder cancer (MIBC) saw significantly improved overall survival (OS) compared to those who had a cystectomy alone, according to a recent study.

Survivorship's Gift to a Mother and Son

November 21st 2017

In the midst of all of the things that tie us together, it’s been what many would consider the most challenging shared experience a mother and son can have – facing and surviving cancer – that has been a defining feature of our relationship and ultimately one of the most overwhelming blessings of life.

Monitoring for Recurrence in Lung Cancer

November 13th 2017

Considerations for Surgery in Lung Cancer

November 13th 2017

The Navigational Bronchoscopy in Lung Cancer

November 13th 2017

Improvements in Detecting Lung Cancer

November 13th 2017

Limitations in Screening for Lung Cancer

November 13th 2017

Multidisciplinary Approach Vital in Bladder Cancer

October 7th 2017

Quality of care for patients being treated for urothelial carcinoma could be improved by having a multidisciplinary team treat the patient, says Robert Jones, M.D.

The Basics Behind Bladder Cancer Treatment Gains

October 5th 2017

“It is not so much that the biology is changing; it’s that our knowledge of the biology is improving,” said Brant Inman, M.D.

Bladder Cancer Treatment Options Continue to Expand

October 2nd 2017

After years with few advancements, five new agents were approved to treat bladder cancer within the last year. CURE spoke with Terence Friedlander, M.D. about the shifting treatment paradigm for patients with the disease.

Educational Resources and Patient Support

September 27th 2017

Improving Outcomes in Bladder Cancer

September 27th 2017

Bladder Cancer Advocacy Network

September 27th 2017

Immunotherapy Experience in Bladder Cancer

September 27th 2017

Bladder Cancer Clinical Trials

September 27th 2017