Bladder Cancer | Tumor

CURE’s bladder cancer page is a go-to resource for oncology news and updates in the world of bladder cancer. Here, readers will find cancer articles, videos, podcasts, and more with expert insight into the latest treatments and research in bladder cancer.

First Patient Receives Novel Antibody in Early-Phase Trial Assessing Safety, Efficacy of the Drug in Several Solid Tumor Types

April 4th 2022

A patient with an advanced solid tumor was given their first dose of a novel antibody, kicking off a phase 1/1b study comparing this drug with or without Keytruda in patients with several types of solid tumors.

First Patient Enrolled Onto Study Evaluating Zepzelca Monotherapy for Treatment of Certain Solid Tumors

March 29th 2022

Approximately 60 patients with metastatic/unresectable solid tumors, including bladder cancer, are expected to be enrolled onto a clinical trial assessing the safety and efficacy of Zepzelca.

First Patient Dosed in Early-Phase Trial Investigating a New Drug for Bladder Cancer

March 25th 2022

The trial will be testing TARA-002 in patients with non-muscle invasive bladder cancer with high-grade carcinoma in situ and high-grade papillary tumors.

‘Today Show’ Anchor Hoda Kotb Discusses Fertility Issues Following Cancer Diagnosis, Pfizer Pulls Blood Pressure Drugs Due to Cancer Concerns and More

March 25th 2022

From Pfizer issuing a voluntary recall of three blood pressure drugs due to a high level of a cancer-causing chemical to “Today Show” co-ancho Hoda Kotb discussing her struggles with fertility after receiving a diagnosis of breast cancer, here’s what’s happening in the cancer space this week.

Male Cancer Caregivers Navigate A Gauntlet of Challenges, Often Under The Cover of Darkness

March 15th 2022

Regardless of a man’s age, providing care to a partner or family member with cancer has been shown to take a drastic toll on their health. To make matters worse, research shows many men struggle in silence.

Immunotherapy Use Increased in Patients Ineligible for Cancer Trials, Highlighting the Need for More Research in Vulnerable Populations

December 28th 2021

The use of immunotherapy in patients with advanced cancers and decreased fitness levels or organ function increased from 2014 to 2019, although trials for this treatment typically exclude this population.

5 Cancer Clinical Trials You May Have Missed

December 18th 2021

There are many cancer clinical trials that patients can enroll in across the United States. Here is a snapshot of some of the more recent ones.

First Patient Receives Novel Immunotherapy in Bladder Cancer Sub-Study

November 13th 2021

The first patient with bladder cancer was dosed in a phase 1/2 trial examining responses to an investigational immunotherapy.

Side Effects From Immune Checkpoint Inhibitors May Increase Hospitalizations, Cost for Patients With Bladder, Liver, Lung or Skin Cancer

November 4th 2021

Patients who experience side effects due to immune checkpoint inhibitors are 80% more likely to go to the emergency room and have 30% higher monthly medical costs, compared to patients who did not have side effects.

New Trial Initiated for Fosciclopirox in Patients With Bladder Cancer

October 26th 2021

A phase 1b trial started to study the effects of fosciclopirox in patients with newly diagnosed and recurrent bladder cancer.

Trial Initiated to Assess Efficacy of Cosela in Bladder Cancer

October 14th 2021

The PRESERVE 3 trial began this summer to determine efficacy of using Cosela with platinum-based chemotherapy in patients with metastatic bladder cancer.

Here’s How Men With Bladder, Colorectal and Prostate Cancer Can Treat Sexual Dysfunction

October 5th 2021

Treatments for bladder, colorectal and prostate cancer may cause sexual dysfunction in men. Here, an expert provides insight into how patients and survivors may improve their sexual health.

Cancer and Ostomies: A World Ostomy Day Perspective

October 2nd 2021

A bladder cancer survivor discusses the importance of World Ostomy Day and shares her own ostomy story.

Here's Why Collaboration Is Important for Progress in Genitourinary Cancers

September 26th 2021

It is important that the whole community understand that basic research and clinical trials can continue to improve outcomes for patients with genitourinary cancer.

Inside the Shifting Treatment Landscape for Advanced Genitourinary Cancers

September 25th 2021

In this special issue of CURE®, we spoke with patients and health care providers about fertility issues, treatment advancements and other topics related to kidney, prostate, testicular and bladder cancers.

New Agent Can Improve BCG Response, Quality of Life in Bladder Cancer

September 18th 2021

The novel drug N-803 boosted response to Bacille Calmette-Guérin therapy in patients with non-muscle invasive bladder cancer, a study showed.

Lack of Smoking Data in Bladder, Kidney and Prostate Cancer Clinical Trials May Affect Patient Outcomes

September 17th 2021

Clinical trials that are designed to ask patients with bladder, kidney and prostate cancer about their smoking status may help patients better understand what to expect from their treatment based on their smoking habits.

Phase 2 BCG-Unresponsive Bladder Cancer Study Gets the OK to Start Enrollment

September 1st 2021

Patients with Bacillus Calmette Guérin-unresponsive carcinoma in-situ will be treated at the University of Chicago in a Theralase study.

FDA Expands Indication of Keytruda for Bladder Cancer Subtype

August 31st 2021

Keytruda is now indicated for the treatment of locally advanced or metastatic urothelial carcinoma, a type of bladder cancer, although an unmet need remains in the treatment of these patients.

FDA’s Recent Approval of Trodelvy Delivers Promising Treatment Option for Metastatic Bladder Cancer

August 23rd 2021

A recently approved antibody-drug conjugate provides another much-needed treatment choice for patients with locally advanced and metastatic urothelial cancer.

Patient Recruitment Has Begun for Trial Assessing Cosela in Metastatic Bladder Cancer

August 20th 2021

Preliminary results of the phase 2 trial assessing the safety and efficacy of Cosela with gemcitabine/platinum-based chemotherapy and Bavencio maintenance therapy for metastatic bladder cancer are expected to be released in the second half of 2022.

FDA Approves Opdivo for Adjuvant Treatment in Bladder Cancer

August 20th 2021

The FDA granted approval to Opdivo as an adjuvant treatment in patients with high-risk urothelial carcinoma.

Bladder Cancer Treatment May Negatively Impact Patients’ Psychosocial Well-being

July 29th 2021

Intravesical therapy for patients with non-muscle invasive bladder cancer was found to have an impact on patients’ social, emotional and physical health.

Vietnam Veteran Discusses Agent Orange Exposure and Bladder Cancer

July 29th 2021

In this episode of the “CURE® Talks Cancer” podcast, a cancer survivor who served in the Vietnam War shares the story of his Agent Orange exposure and bladder cancer.

Continuing to Smoke After Bladder Cancer Diagnosis Increases Recurrence Risk

July 20th 2021

Smoking cigarettes could lead to a four-fold increased risk of recurrence in patients with a previous diagnosis of non-muscle invasive bladder cancer.

Glycemic Index, But Not Glycemic Load or Carb Intake, May Increase Bladder Cancer Risk

July 19th 2021

An analysis showed that glycemic index – but not glycemic load or total carbohydrate intake – significantly increased the risk of developing bladder cancer.

FDA Grants Regular Approval to Padcev for Pretreated Metastatic or Advanced Bladder Cancer

July 9th 2021

Approximately 18 months after granting Padcev an accelerated approval, the Food and Drug Administration granted a regular approval to the treatment for certain previously treated patients with locally advanced or metastatic urothelial carcinoma.

Patients Should Ask Their Providers About Clinical Trial Results

July 7th 2021

Results demonstrating the efficacy of Bavencio highlight the importance of incorporating recent clinical trial successes into the treatment conversation.

VA Adds Bladder Cancer as Potential Effect of Agent Orange Exposure

July 7th 2021

Agent Orange exposure impacted millions of U.S. military personnel during the Vietnam War. The chemical may have led to bladder cancer diagnoses later in life.

Trimodality Treatment Including Keytruda May Provide Non-Surgical Treatment Option for Subset of Bladder Cancer

July 4th 2021

Keytruda plus gemcitabine and higher doses of radiotherapy showed promising efficacy and safety results in patients with muscle-invasive bladder cancer.