Uproleselan Fails to Improve Survival in AML, Although Some Subgroups May Benefit
A Phase 3 trial of uproleselan failed to improve overall survival in relapsed/refractory AML, though it may benefit primary refractory patients.
Read More
Venclexta Plus Mavenclad Boosts Response Rates in AML, MDS
The Venclexta-based regimen improved complete response rates in patients with acute myeloid leukemia and myelodysplastic syndromes.
Heart Risk May Occur Less With Some BTK Inhibitors in B-Cell Blood Cancers
In patients with certain B-cell blood cancers, heart-related side effects may occur less after receiving second-generation BTK inhibitors.
Brukinsa Supported as First-Line Treatment for Patients With CLL/SLL
Patients with treatment-naive CLL/SLL experienced long-term improved efficacy when treated with Brukinsa compared with bendamustine plus Rituxan.
Pelabresib Plus Jakafi Maintains Efficacy in JAK-Naive Myelofibrosis
Adding pelabresib to a JAK inhibitor may improve multiple aspects of myelofibrosis, including spleen size, symptoms and bone marrow fibrosis.
Tecvayli Effective Maintenance Therapy in Newly Diagnosed Multiple Myeloma
Tecvayli alone or plus Revlimid has been found to be safe and may result in high MRD-negativity rates.
Darzalex Faspro May Improve Progression, Survival in Smoldering Multiple Myeloma
The risk for disease progression or death was reduced by 51% with subcutaneous Darzalex Faspro in certain patients with smoldering multiple myeloma.
Calquence Plus Venclexta Combo May Improve Survival in Frontline CLL
Calquence plus Venclexta, with or without Gazyva, improved progression-free survival over the standard-of-care chemoimmunotherapy in patients with untreated chronic lymphocytic leukemia.
Scemblix May Outperform Standard Treatments for Chronic Myeloid Leukemia
Scemblix resulted in better outcomes and fewer side effects compared to standard tyrosine kinase inhibitor therapies in patients with chronic myeloid leukemia.
Navtemadlin Shows Biomarker Response in Patients with R/R Myelofibrosis
Patients with relapsed or refractory (R/R) myelofibrosis experienced reduced biomarkers of disease severity following treatment with navtemadlin.
Tecartus Shows Similar Efficacy Across Age Groups in Leukemia
Tecartus demonstrated similar effectiveness across age groups of patients with relapsed or refractory B-cell acute lymphoblastic leukemia.
Revuforj Continues to Elicit Meaningful Responses in Some With Acute Leukemia
Long-term follow-data shows Revuforj to be effective in the treatment patients with R/R KMT2Ar acute leukemias.
D-VRd May Improve Minimal Residual Disease Responses in Multiple Myeloma
For patients with transplant-ineligible or -deferred newly diagnosed multiple myeloma, the addition of Darzalex to VRd improved MRD responses as well as progression-free survival.
Smoking May Be Linked With Genetic Mutations, Progression Risk in MDS
Results from the study also showed the potential association between smoking, disease progression and survival in patients with myelodysplastic syndromes.
CAR-T Cell Therapy Shows EFS Benefit in Pediatric Leukemia Subset
Treatment with bicistronic CD19/CD22 CAR-T cell therapy has shown event-free survival improvements in children with relapsed or refractory B-ALL.
Blincyto With Chemo May Improve Disease-Free Survival in Pediatric B-ALL
Pediatric patients with standard-risk B-ALL demonstrated significantly improved disease-free survival with Blincyto plus chemotherapy versus chemotherapy alone.
Overcoming Hormone Therapy Resistance in Metastatic Breast Cancer
An expert discusses the next steps for patients with metastatic breast cancer after their disease no longer responds to hormone therapy.
Watch
Jemperli-Chemo Regimen Shows Survival Promise in Advanced NSCLC
In patients with advanced NSCLC, treatment with Jemperli plus chemotherapy showed promising effectiveness compared with Keytruda plus chemotherapy.
Common Prostate Cancer Radiation Questions Answered
Expert answers to patients’ questions were offered as part of the CURE® Educated Patient® Prostate Cancer Summit.
Balancing Decisions Around Breast Cancer Treatment and Fertility, Breastfeeding
An expert discussed how patients with breast cancer, particularly those with a BRCA mutation, should consider future fertility and breastfeeding when making treatment decisions.
Monitoring Treatment With Different Types of Biopsies in Lung Cancer
An expert discussed how liquid and tissue biopsies can help monitor treatment and detect potential resistance in patients with non-small cell lung cancer.
Regular Check-Ups Provide Necessary Support During Breast Cancer Survivorship
Through regular follow-ups and symptom assessments, breast cancer survivors have the access to physical and emotional support they may need.
Discussing Radiation as a Treatment Option for Kidney Cancer
An expert explained the advantages and disadvantages of radiation as a treatment for patients with renal cell carcinoma, a type of kidney cancer.
Treatment Side Effects, Quality of Life Factors in Prostate Cancer
It’s crucial for patients with prostate cancer to know that all treatments come with side effects, which may affect their quality of life.
Rise in PSA Levels May Predict Treatment Response in Prostate Cancer
The rate at which PSA rises after hormonal therapy for prostate cancer is a key factor in determining the effectiveness of the treatment.
‘Not Enough to Say Breast Cancer’ When Discussing Diagnoses, Expert Says
An expert discussed the importance of patients learning about their specific type of breast cancer to understand potential treatment options.
Resistance Mechanisms May Steer Therapy Sequences in EGFR-Mutated Lung Cancer
An expert discussed how the understanding of resistance mechanisms can help care teams develop a global treatment strategy for EGFR-mutated non-small cell lung cancer.
Focal Therapy May Reduce Side Effects, Improve Quality of Life in Prostate Cancer
With approaches like high intensity focused ultrasound, patients with prostate cancer may experience lower rates of urinary incontinence and erectile dysfunction, an expert said.
Next-Generation Imaging a ‘Gold Standard’ in Metastatic Prostate Cancer
Patients with metastatic prostate cancer may have improved survival outcomes after undergoing next-generation PSMA PET imaging, an expert explained.
Fertility Preservation Options for Young Patients With Breast Cancer
An expert discussed options young patients with breast cancer may have to preserve their fertility before starting cancer treatment.