Opdivo Before and After Surgery Improves Event-Free Survival in NSCLC
Some patients with stage 3 non-small cell lung cancer saw benefits from Opdivo plus chemotherapy followed by surgery then Opdivo, researchers found.
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Dato-DXd Improves Antitumor Intracranial Responses in NSCLC Subgroups
Dato-DXd was efficacious in patients with non-small cell lung cancer with brain metastases who have certain gene alterations, a phase 2 study showed.
Vaccine-Based Combo Shows Disease Control in CRC
PolyPEPI1018 may boost the efficacy of Tecentriq in certain patients with colorectal cancer.
Belamaf Regimen Improves Progression-Free Survival in Myeloma
Belamaf plus bortezomib and dexamethasone lengthened the time patients with relapsed or refractory myeloma lived before their disease got worse.
Bile Duct Cancer Continues to Respond to Zanidatamab, Per Longer Follow-Up
Zanidatamab continued to lead to responses and improved overall survival in pretreated HER2-positive biliary tract cancer.
Reblozyl Continues to Improve MDS Transfusion Independence
Patients with myelodysplastic syndromes tended to have longer periods of time without needing a red blood cell transfusion when treated with Reblozyl.
An Expert Breakdown of SurVaxM, the Novel Brain Cancer Vaccine
SurVaxM, which is being studied in gliobastoma, targets a certain protein that is found on the brain cancer cells.
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Safety Profile of Lower-Dose Oral Onureg Remains Consistent in Lower-Risk MDS
The safety profile of 200 milligrams and 300 milligrams of oral Ongureg were similar in patients with lower- to intermediate-risk MDS.
Enhertu Boosts PFS in Pretreated, HR-Positive, HER2-Low and -Ultralow Breast Cancer
Enhertu lengthened the time to progression in patients with HR-positive, HER2-low or -ultralow metastatic breast cancer.
Chemo, Targeted Drugs Extremely Efficacious in HER2-Positive Breast Cancer
Presurgical paclitaxel, Herceptin and Perjeta showed “incredible efficacy” in treatment of HER2-positive breast cancer.
Perioperative Chemo Shows Longer Survival in Esophageal Cancer
Perioperative chemotherapy with chemotherapy led to improved survival outcomes versus neoadjuvant chemoradiation in resectable esophageal cancer.
Blenrep Combo Lengthens Time to Progression in Relapsed, Refractory Myeloma
Blenrep, Pomalyst and dexamethasone improved progression-free survival compared to Velcade, Pomalyst and dexamethasone in patients with relapsed/refractory myeloma.
Neoadjuvant Opdivo Plus Yervoy Provides ‘Excellent Responses’ in Stage 3 Melanoma
Opdivo plus Yervoy in the neoadjuvant setting reduced the risk for recurrence, progression or death, potentially offering patients with stage 3 melanoma a new standard of care.
Tagrisso Could Become Standard of Care for Some With EGFR+ NSCLC
Tagrisso following chemoradiotherapy improved progression-free survival compared with placebo in stage 3 EGFR-mutated non–small cell lung cancer.
Lymphadenectomy Didn’t Improve Progression, Survival in Ovarian Cancer
Researchers found that adding retroperitoneal lymphadenectomy to cytoreductive surgery did not improve survival among patients with advanced ovarian cancer.
Palliative Care via Telehealth Similarly Beneficial to Quality of Life in Lung Cancer
Researchers found telehealth care to deliver comparable quality-of-life benefits versus in-person visits among patients with advanced non-small cell lung cancer.
Posttreatment Imfinzi Sets New Standard for Small Cell Lung Cancer
For the first time in decades, a new regimen — consolidation Imfinzi after chemoradiation — improved outcomes in patients with limited-stage small cell lung cancer.
Rybrevant Plus Leclaza Has ‘Very Potent Activity’ in Lung Cancer Subset
Rybrevant plus Leclaza had promising response and progression-free survival rates in patients with EGFR-mutant non-small cell lung cancer.
Long-Term Follow-Up Still Shows Tafinlar/Mekinist Benefit in Melanoma
Eight-year follow-up showed that Tafinlar plus Mekinist continued to improve outcomes for patients with stage 3 melanoma.
Rybrevant Plus Leclaza May Be New Standard for EGFR-Mutant Lung Cancer
Rybrevant plus Leclaza outperformed Tagrisso regarding progression-free survival in patients with EGFR-mutant non-small cell lung cancer.
Adcetris Regimen Outperforms Intense Chemo in Classical Hodgkin Lymphoma
An Adcetris-based treatment regimen improved progression-free survival and was more tolerable for patients with classical Hodgkin lymphoma.
Lorbrena Shows Longest Progression-Free Survival in Advanced NSCLC
Lorbrena demonstrated longer progression-free survival and improved time to intracranial progression, compared with Xalkori in ALK-positive non-small cell lung cancer.
Positive Scemblix Data ‘May Change the Treatment Paradigm in CML’
Scemblix outperformed standard tyrosine kinase inhibitor treatment in patients with Philadelphia chromosome-positive chronic myeloid leukemia.
Conjugated Equine Estrogen Increases Gynecologic Cancer Death Rates
Postmenopausal patients with ovarian or endometrial cancer who received conjugated equine estrogen may have increased mortality rates.
HPV Vaccines Associated With Lower Cancer Risk in Younger Adults
When compared with unvaccinated patients, HPV vaccines were associated with lower rates of HPV-related cancer for people younger than 40.
AI Navigation May Help Patients Schedule Missed Colonoscopies
An artificial intelligence-based navigation tool may be used to call patients who previously missed their colonoscopy appointment with the goal that they will reschedule and attend the new appointment.
Most Patients Attempting Pregnancy After Breast Cancer Succeed
In a group of breast cancer survivors, 73% who attempted pregnancy were successful, though there were certain characteristics associated with an increased chance of getting pregnant.
Easing a Hospital Stay for a Patient With Cancer as an Oncology Nurse
Jessica McDade, B.S.N., RN, OCN, explains how she helps make her patients’ experience “a little less daunting” during their hospital stay.
Nurse Says CAR-T Cell Therapy is a ‘Mind-Blowing’ Advancement
For patients with blood cancers, CAR-T cell therapy has been a “mind-blowing” advancement for treatment in the cancer space.
Genetic Testing for Breast Cancer May Benefit Family Members
An expert explained that patients with breast cancer who undergo genetic testing may help their family members, regardless of whether patients have children.