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Rubraca Granted Breakthrough Designation for Prostate Cancer
October 2nd 2018The FDA has granted the PARP inhibitor Rubraca (rucaparib) a breakthrough therapy designation for single-agent use in adult patients with BRCA1/2-positive metastatic castration-resistant prostate cancer (mCRPC) following at least one androgen receptor–directed therapy and taxane-based chemotherapy.
How I'm Handling Pinktober This Year
October 2nd 2018Pinktober heralds the arrival of so much pink that some of us run screaming from the sight of it, despite the good intentions of Breast Cancer Awareness Month. As I explain how I have made my peace with pink, you might feel better about your own choices.
FDA Approves Libtayo for Cutaneous Squamous Cell Carcinoma
September 29th 2018The FDA has approved the PD-1 inhibitor Libtayo (cemiplimab) for the treatment of patients with metastatic cutaneous squamous cell carcinoma (CSCC) or patients with locally advanced CSCC who are not candidates for curative surgery or curative radiation.
Preventing Myelofibrosis from Progressing to Acute Myeloid Leukemia
September 28th 2018Diagnosing and treating the disease before it turns into AML is a key area of study, said Srdan Verstovsek, M.D., Ph.D., medical oncologist and professor in the Department of Leukemia at The University of Texas MD Anderson Cancer Center.
FDA Approves Vizimpro for EGFR-Positive Lung Cancer
September 28th 2018The Food and Drug Administration (FDA) has approved Vizimpro (dacomitinib) for the frontline treatment of patients with metastatic non–small cell lung cancer (NSCLC) with EGFR exon 19 deletion or exon 21 L858R substitution mutations, according to Pfizer, the manufacturer of the pan-human EGFR tyrosine kinase inhibitor (TKI).
Concurrent Tecentriq Adds First Survival Benefit Seen in Small Cell Lung Cancer in 20 Years
September 25th 2018The IMpower133 trial demonstrated the added overall and progression-free survival benefits of adjuvant Tecentriq with standard of care therapy for patients with extensive-stage small cell lung cancer.