Breast Cancer | Tumor

CURE’s breast cancer page is an extensive resource of cancer information featuring the latest breast cancer news, expert oncologist insights on the latest cancer treatments, oncology research, advocacy efforts, and medical data on breast cancer.

FDA Speeds Up Review of Enhertu for Previously Treated Unresectable/Metastatic HER2-Breast Cancer

January 17th 2022

After the drug showed promising results in the DESTINY-Breast03 trial, the FDA granted Enhertu a priority review, meaning that it plans to make its approval decision on it by the end of the second quarter of 2022.

How Can We Get Young Women to Get Annual Mammograms?

January 17th 2022

One breast cancer survivor shares the experience she had with her daughters in trying to get them to understand the importance of participating in preventive screenings.

Higher BMI in Adulthood May Limit the Immune System’s Ability to Fight Breast Cancer

January 14th 2022

New findings demonstrated that adult patients with breast cancer and increased BMI had an association with different types of immune cells around their tumors that may affect how their body attacks the cancer cells.

FDA Target Dates for Potential Cancer Drug Approvals in Early 2022

January 10th 2022

The Food and Drug Administration is expected to decide on whether to approve certain cancer regimens within the first few months of the year. Here’s what patients with cancer should know.

Keytruda/Chemo Combo Is ‘Great News’ for Patients With TNBC, ‘But We Need Much More’

January 6th 2022

An expert discusses improvements in survival outcomes for patients with triple-negative breast cancer who received Keytruda plus chemotherapy — now considered the standard of care — but urges that more researched is always needed for this patient population.

Aromatase Inhibitors Reduce Recurrence Risk, But Not Death Rates, in Premenopausal Patients With Breast Cancer

January 5th 2022

Premenopausal women with ER-positive breast cancer experienced a decreased rate of recurrence when given an aromatase inhibitor, compared with those given tamoxifen. However, more research is still needed, an expert said.

Novel Drug Combo Induces Encouraging Results in Patients With Heavily Pretreated Breast Cancer

January 3rd 2022

The use of Faslodex plus the investigational drug samuraciclib was considered safe in individuals with heavily pretreated hormone receptor-positive breast cancer.

Cancer Drug Approvals from 2021 That Patients May Have Missed

December 28th 2021

2021 was full of research advancements and FDA drug approvals that continue to improve cancer care for patients with a variety of malignancies.

Second-Line Enhertu May Be ‘Standard of Care’ for Patients with HER2-Positive Metastatic Breast Cancer

December 28th 2021

The use of Enhertu may also be beneficial across HER2-positive metastatic breast cancer subgroups including patients with and without brain metastases.

Study Results Champion Keytruda/Chemo as ‘New Standard of Care’ in TNBC Subset

December 27th 2021

The combination of Keytruda and chemotherapy improved survival rates in patients with PD-L1—positive metastatic triple-negative breast cancer.

The 5 Most-Read Breast Cancer Articles of 2021

December 22nd 2021

CURE® takes a look back at its top-performing breast cancer articles of 2021.

Metastatic Breast Cancer: ‘It’s What You Can’t See That’s Killing Me’

December 21st 2021

A woman with metastatic breast cancer writes a poem about the dark reality of the disease that hides below the surface.

Pre-Surgical Keytruda Provides Promising Advancement in TNBC Treatment

December 20th 2021

Findings from a clinical trial showed that adding Keytruda to neoadjuvant chemotherapy in patients with triple-negative breast cancer significantly improved outcomes and was overall safe and tolerable for patients.

5 Cancer Clinical Trials You May Have Missed

December 18th 2021

There are many cancer clinical trials that patients can enroll in across the United States. Here is a snapshot of some of the more recent ones.

Male Breast Cancer Survivor Went From Feeling Alone to Feeling Connected to All Survivors

December 17th 2021

One male breast cancer survivor explains why he considers his cancer experience an “adventure into the unknown,” where he draws inspiration from every survivor he meets.

Oncolytic Virus Clinical Trial Opens for Patients With Advanced Breast Cancer

December 17th 2021

City of Hope has opened its first-in-human clinical trial for an investigational therapy in patients with advanced breast cancer.

Lynparza After Chemo May Not Greatly Impact Quality of Life in High-Risk Early Breast Cancer Subset

December 11th 2021

Although patients treated with Lynparza after chemotherapy may experience side effects such as fatigue and nausea/vomiting, these symptoms resolved after treatment was completed in patients with high-risk early breast cancer.

Triplet Regimen Extends Time Before Brain, Spinal Cord Metastases Worsen in Patients With Breast Cancer

December 10th 2021

A three-drug regimen was shown to lengthen the amount of time before cancer progressed to the central nervous system — known as central nervous system progression-free survival — in certain patients with breast cancer.

Experimental Drug Plus Chemo Boosts Survival in HER2-Positive Metastatic Breast Cancer

December 10th 2021

The use of pyrotinib — an experimental drug — plus the chemotherapy capecitabine extended survival compared with Tykerb and capecitabine among patients with pretreated HER2-positive metastatic breast cancer.

Novel Drug Elicits Favorable Outcomes in Advanced, Metastatic TNBC

December 10th 2021

Early-phase study results showed that treatment with a novel drug elicits promising outcomes in patients with advanced or metastatic triple-negative breast cancer.

Immunotherapy Before Surgery May ‘Increase the Chances’ Patients Are Cured of TNBC

December 9th 2021

Clinical trial results show that adding Keytruda to chemotherapy prior to surgery for triple-negative breast cancer can improve outcomes and hopefully “increase the chances for patients to be cured,” according to an expert.

Black Patients More Likely to Experience Treatment Changes That May Worsen Breast Cancer Outcomes

December 9th 2021

Treatment modifications in the pre-surgery setting led to a lower rate of pathologic complete response in Black patients with breast cancer, the researchers found.

Study Confirms Adding Ibrance to Endocrine Therapy May Not Improve Outcomes in Early Breast Cancer

December 8th 2021

The addition of Ibrance to endocrine therapy was not associated with preventing disease recurrence in patients with hormone receptor (HR)–positive, human epidermal growth factor receptor 2 (HER2)–negative early breast cancer, according to final results of the phase 3 PALLAS trial.

Medication Used to Treat Diabetes Fails to Improve Breast Cancer Outcomes

December 8th 2021

Researchers hypothesized that metformin — a medication that helps lower insulin levels in patients with diabetes and is associated with inducing weight loss — might improve breast cancer outcomes.

Novel Drug Has Potential to ‘Become New Standard of Care’ in Advanced, ER-Positive Breast Cancer

December 8th 2021

The use of elacestrant, an investigational therapy, elicited a 30% reduction in the risk of disease progression or death compared with standard of care in a group of patients with estrogen receptor (ER)–positive, HER2-negative metastatic breast cancer.

Novel Drug Combo Doubles Progression-Free Survival in HER2-Negative Metastatic Breast Cancer

December 7th 2021

Ibrance plus Faslodex improved progression-free survival in certain patients with metastatic breast cancer, compared with those who continued to receive an aromatase inhibitor.

Black Women With Breast Cancer Have a Higher Risk of Developing Lymphedema Than White Women

December 7th 2021

Black race is associated with a 3.5-fold increased incidence of lymphedema in women with breast cancer treated with axillary lymph node dissection and radiotherapy, according to recent data.

CURE® Honors Patients, Advocates, Oncologist in Inaugural Metastatic Breast Cancer Heroes™ Award Program for Increasing Awareness

December 7th 2021

CURE’s Metastatic Breast Cancer Heroes™ Award Program expresses gratitude to the heroes who impact the lives of patients with metastatic breast cancer.

What a Mother of a Cancer Survivor Really Wants for Christmas

December 6th 2021

A mother of a young breast cancer survivor shares the letter she wrote to Santa explaining her only Christmas wish.

The Ins and Outs of Risk Stratification, Managing Side Effects and Survivorship in Breast Cancer

December 6th 2021

Patients who understand their roles and responsibilities may better help their care teams understand what they may be at risk for in their cancer survivorship.