Opinion|Videos|January 5, 2024

Adverse Events Seen With JAK Inhibitors for Myelofibrosis

The JAK inhibitors approved for myelofibrosis have common side effects of cytopenias and gastrointestinal issues, with additional risks of weight gain and cardiac effects and diarrhea; momelotinib and pacritinib show improved tolerability compared to earlier JAK inhibitors.

Related to this article

Image of Ramshaw
After a pancreatic cancer diagnosis upended his life and career, one survivor reflects on treatment, resilience and finding hope more than a decade later.