Do You See What I See?
December 08, 2013 – Emily Morrison
Pancreatic Cancer Advocates Unite
December 08, 2013 – Julie Fleshman
Pipeline
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The Challenges of Distance Caregiving
December 09, 2013 – Jane Hill
Adult Siblings Often Coordinate Parental Support
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What Could Cause Cognitive Dysfunction after Cancer?
December 09, 2013 – Kathy LaTour
Pharmacologic Approaches to Cognitive Dysfunction
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Finding Solutions for Chemobrain
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Late Effects & Premature Aging After Pediatric Cancer
December 09, 2013 – Don Vaughan
Health Problems Common in Survivors of Pediatric Cancer
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Post-Mastectomy Pain Hits a Nerve
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Advances in Screening & Early Detection of Pancreatic Cancer
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Changing Course in Pancreatic Cancer
December 09, 2013 – Roxanne Nelson
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Solving the Treatment Resistance Riddle
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For Caregivers: Tips Before Planning that "End of Treatment" Party
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Why Observing Treatment Milestones is an Individual Decision
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Is Robot-Assisted Surgery the Best Treatment for Your Cancer?
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How I Lost My Uterus and Found My Voice
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Website Retooled to Help Visitors Navigate Medicare
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Michael Douglas Reveals He Had Tongue Cancer
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ASH Updates
December 08, 2013 – Elizabeth Whittington
Message From the Editor
December 09, 2013 – Debu Tripathy, MD
Letters From Readers
December 08, 2013
Do You See What I See?
December 08, 2013 – Emily Morrison
Pancreatic Cancer Advocates Unite
December 08, 2013 – Julie Fleshman
Pipeline
December 09, 2013 – Lindsay Ray
The Challenges of Distance Caregiving
December 09, 2013 – Jane Hill
Adult Siblings Often Coordinate Parental Support
December 09, 2013 – Jane Hill
What Could Cause Cognitive Dysfunction after Cancer?
December 09, 2013 – Kathy LaTour
Pharmacologic Approaches to Cognitive Dysfunction
December 09, 2013 – Kathy LaTour
Finding Solutions for Chemobrain
December 08, 2013 – Kathy LaTour
Post-Traumatic Stress Disorder after Childhood Cancer
December 09, 2013 – Don Vaughan
Late Effects & Premature Aging After Pediatric Cancer
December 09, 2013 – Don Vaughan
Health Problems Common in Survivors of Pediatric Cancer
December 09, 2013 – Don Vaughan
Post-Mastectomy Pain Hits a Nerve
December 09, 2013 – Lacey Marlow
Currently Viewing
Advances in Screening & Early Detection of Pancreatic Cancer
December 09, 2013 – Roxanne Nelson
Tumor Evolution
December 08, 2013 – Katy Human
Solving the Treatment Resistance Riddle
December 09, 2013 – Katy Human
For Caregivers: Tips Before Planning that "End of Treatment" Party
December 09, 2013 – Charlotte Huff
Why Observing Treatment Milestones is an Individual Decision
December 09, 2013 – Charlotte Huff
Searching for an Oncology Surgeon
December 08, 2013 – Katherine Hobson
Is Robot-Assisted Surgery the Best Treatment for Your Cancer?
December 08, 2013 – Katherine Hobson
How I Lost My Uterus and Found My Voice
December 09, 2013 – Kathy LaTour
Personalized Medicine Should Include High-Quality, High-Value Care
December 09, 2013 – Len Lichtenfeld, MD
Website Retooled to Help Visitors Navigate Medicare
December 08, 2013 – Jon Garinn
Poor Kidney Function a Possibility in Adult Survivors of Childhood Cancer
December 09, 2013 – Katherine Lagomarsino
Dispatch: Society for Integrative Oncology's 10th Annual Meeting
December 09, 2013 – Debu Tripathy, MD
Reel Recovery Retreats
December 09, 2013 – Jon Garinn
Studies Confirm Effectiveness of Colorectal Cancer Screening
December 09, 2013 – Elizabeth Whittington
Michael Douglas Reveals He Had Tongue Cancer
December 09, 2013 – Lindsay Ray
Dose of Reality Effective at Stopping Smokers
December 09, 2013 – Lena Huang
FDA's Breakthrough Therapy Designation Aims to Speed Drug Approvals
December 08, 2013 – Susan Jenks
ASH Updates
December 08, 2013 – Elizabeth Whittington
Message From the Editor
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Advances in Screening & Early Detection of Pancreatic Cancer

Early research shows promise in screening and detecting pancreatic cancer at its earliest stages.

BY Roxanne Nelson
PUBLISHED December 09, 2013

Scientists have identified a serum protein that shows distinct changes in structure among those with pancreatic cancer compared with healthy individuals. The protein, haptoglobin, and the way it binds to other proteins, also changes between earlystage and advanced disease.

These findings suggest it might be possible to develop a blood test that could be used to screen individuals at high risk of the disease and to detect it at an earlier stage.

Another potential blood test uses metabolomics analysis, an emerging science focusing on small molecules called metabolites, which are products of metabolism and atypical in cancer. This test measures the metabolites found in the blood.

Researchers at the Mayo Clinic in Rochester, Minn., are looking at a completely different way of early disease detection. They are evaluating testing stool for methylations, a type of DNA modification strongly associated with cancers and pre-cancers. Early results are promising, as methylation markers were detected in stool samples, regardless of the stage or location of the cancer.

Finally, another area of interest is pancreatic cysts. Cysts are generally benign, but some eventually progress to malignancy. Many promising tests are under development to help differentiate a benign from a malignant cystic tumor. If validated, these tests may be used as an another tool to the conventional workup of pancreatic cysts to help better guide patient management and decisions about the need for surgical resection.

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