The FDA has withdrawn its accelerated approval of Krazati combined with Erbitux for adults with KRAS G12C-mutated colorectal cancer that is locally advanced or has spread to other parts of the body.
Press Release|Articles|September 15, 2026
Bottoms Up® Invitational Raises $5.7 Million in Five Years To Foster a Future Free From CRC
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Key Takeaways
- The Bottoms Up® Invitational combined a concert and golf-centered activities to mobilize public attention and philanthropic capital for colorectal cancer, raising over $5.7 million in five years.
- Early-onset colorectal cancer trends were emphasized, including projections of a 90% increase in incidence among ages 20–39 by 2030 and persistently high late-stage diagnoses.
The fifth annual Bottoms Up® Invitational, organized by Today Show anchor Craig Melvin and CBS Sports HQ host Lindsay Czarniak, gathered a passionate crowd of celebrities, musicians, athletes and supporters to raise awareness and funds in the battle against colorectal cancer.
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The fifth annual Bottoms Up® Invitational, organized by Today Show anchor Craig Melvin and CBS Sports HQ host Lindsay Czarniak, gathered a passionate crowd of celebrities, musicians, athletes and supporters to raise awareness and funds in the battle against colorectal cancer. The two-day event honors the memory of Craig’s brother, Lawrence Meadows, who died from the disease at age 43. Colorectal cancer is the deadliest cancer in people under age 50, with 75% diagnosed at late stages when options are limited and survival rates drop. The event brings attention and much-needed funds to the disease, raising more than $5.7 million over five years in support of the lifesaving work of the Colorectal Cancer Alliance (Alliance), the nation’s largest nonprofit dedicated to ending the disease.
The fifth anniversary extravaganza kicked off September 13 with a lively concert at the Fairfield Theatre Company, featuring performances by Wyclef Jean, Chris Barron from the Spin Doctors, Andrew Copeland & Jett Beres of Sister Hazel, Branford Marsalis, Javier Colon, Ryan Cabrera, and more, celebrating hope for a world free from colorectal cancer. On September 14, participants enjoyed entertaining activities with celebrity guests including Dylan Dreyer, Willie Geist, Jim Cantore, Rutledge Wood, Stephanie Szostak, Ralph Sampson, Charlie Rymer, Allan Houston, and others at Shorehaven Golf Club in Norwalk, CT, to drive funds for the cause.
The support comes at a critical time. Colorectal cancer is one of the fastest growing cancers in people under age 50 and cases among Americans ages 20 to 39 are projected to increase by 90 percent by 2030. Prior to the concert, medical and industry experts joined Craig at the Alliance’s
"We are in a race against a disease that is skewing younger and more aggressive every year," said Michael Sapienza, CEO of the Colorectal Cancer Alliance. "Craig and Lindsay chose to turn their loss into action and are creating tremendous impact. Every dollar raised moves us closer to a future where we can end colorectal cancer and ensure more families stay whole. We’ve had enough - let’s end this”
Proceeds from the event will benefit the work of the Alliance through programs like
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