A new large national study led by researchers atthe American Cancer Society (ACS) shows the mortality risk from cardiovascular disease (CVD) differs considerably among cancer survivors by race/ethnicity and cancer types. The findings will be presented at this year’s annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago, June 3-7.
The results showedamong 2,806,515 survivors (NHW, 68%; NHB, 13%; Hispanic, 12%; API, 7%; AI, 0.5%), 57,883 CVD deaths occurred during 6.4 person-years of mean follow-up. Cancer survivors overall were at increased risk of CVD death compared to the general population with an SMR of 1.76 among API, 1.49 among AI, 1.46 among Hispanic, 1.30 among NHB, and 1.13 among NHW survivors. Compared with NHW survivors, the adjusted hazard of CVD death was statistically significantly higher among NHB survivors for 23/23 cancers and among AI survivors for 9/18 cancers but was statistically significantly lower among Hispanic survivors for 5/23 cancers and among API survivors for 10/23 cancers, with no significant difference otherwise. The highest hazard ratios (HRs) were among NHB survivors of melanoma; breast; pancreatic; and testicular cancers, whereas the lowest HRs were among API survivors of head and neck and cervical cancers and Hispanic survivors of cervical cancer.
Study authors highlight the need for targeted prevention and surveillance in primary care and for future studies to identify factors that contribute to this variation to inform efforts towards mitigating risk.
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