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The addition of the investigational PI3K inhibitor pictilisib to the aromatase inhibitor Faslodex in patients with metastatic breast cancer yielded some intriguing findings in the FERGI study.


Early Phase Study Finds PI3K Inhibitor Pictilisib Helps a Subset of Advanced Breast Cancer Patients

Unmet Needs and Challenges in Metastatic Uveal Melanoma

Video content above is prompted by the following:

As a patient advocate, what are some challenges that patients face that you wish to highlight?

What are the unmet needs for this population?

What advice do you have for patients and caregivers?

Experts discuss unmet needs and challenges faced by patients with uveal melanoma.

This program was made possible with support from Immunocore.

Video Series

CURE Expert Connections

Safety and Efficacy of Tebentafusp

Please discuss recent updates for tebentafusp.

Have you had clinical experience with tebentafusp? If so, please comment.

What mitigation strategies do you implement to manage side effects?

What do patients need to understand about the black box warning about cytokine release syndrome?

Nathan L. Scott, M.D., discusses the safety and efficacy of tebentafusp.

This program was made possible with support from Immunocore.

Choosing the Appropriate Treatment for Metastatic Uveal Melanoma

Provide a brief overview of the current guidelines for the treatment of metastatic uveal melanoma.

How has the approval of tebentafusp impacted the treatment landscape?

How do you determine the right treatment for each patient?

Provide a brief overview of the mechanism of action of tebentafusp. Which patients are eligible for this treatment? 

Why is it important for patients to know if they are HLA-A*02:01 positive?

For patients not eligible for tebentafusp, what are your recommendations?

As an advocate, how would you advise patients on how to approach selecting the best treatment option?

What factors impact patients’ treatment selection, and what barriers do they face when selecting a treatment?

How do you encourage patients to advocate for themselves when making decisions for their treatment? 

General query for these questions: Should they say the patient would work with their doctor to select best treatment for their situation?

Nathan L. Scott, M.D., provides a brief overview of the current guidelines for treatment of metastatic uveal melanoma, as well as what considerations go into choosing the appropriate treatment for it. 

This program was made possible with support from Immunocore.

Uveal Melanoma Prognosis and Risk Stratification

For patients diagnosed with uveal melanoma, what is the prognosis and the risk of recurrence?

Briefly discuss the risk class levels and what strategies are implanted for monitoring.

When uveal melanoma spreads, what are the common sites of metastasis?

What are some concerns that patients have?

Nathan L. Scott, M.D., discusses the risk of recurrence within diagnosed uveal melanoma patients. 

Uveal Melanoma Prognosis and Risk Stratification

Resources for Patients With Newly Diagnosed Uveal Melanoma 

How do you educate your patients who have been recently diagnosed

What resources do you provide for patients who have been just diagnosed?

Melody Burchett discusses how she educates patients who have been recently diagnosed with uveal melanoma. 

Resources for Patients With Newly Diagnosed Uveal Melanoma

Diagnosing Uveal Melanoma

If uveal melanoma is suspected, what tests should a patient expect to undergo to confirm diagnosis?

At what point in the disease stage is the patient referred from an ophthalmologist to an oncologist?

Nathan L. Scott, M.D., details what tests a patient should expect if they wish to confirm a uveal melanoma diagnosis.

This program was made possible with support from Immunocore.

Lauren M. Green

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