April 17, 2018 – Patrick Dempsey
April 10, 2018 – Jeanne M. Palmer, M.D.
April 06, 2018 – Thea's Star of Hope
March 19, 2018 – John Marshall, M.D.
March 15, 2018 – William J Gradishar, M.D.
March 14, 2018 – Jane N. Winter, M.D.
March 13, 2018 – Jarushka Naidoo, MBBCh
March 12, 2018 – Sagar Lonial, M.D.
March 09, 2018 – John Marshall, M.D.
March 07, 2018 – Ruben Mesa, M.D.
February 26, 2018 – Joshua Bauml, M.D.
January 30, 2018 – William G. Wierda, M.D., Ph.D.
January 26, 2018 – Joshua Richter, M.D.
January 23, 2018 – Michael J. Overman, M.D.
January 22, 2018 – Tom Stockwell
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January 19, 2018 – Marina Chiara Garassino, M.D.
January 19, 2018 – Carole Brennan Miller, M.D.
January 17, 2018 – Julie R. Libon
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January 13, 2018 – Susan Leclair, Ph.D., CLS (NCA)
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January 05, 2018 – Lindsey M. Lyle, M.S.
January 04, 2018 – Barbara Abernathy, Ph.D.
January 03, 2018 – Martha Raymond
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December 19, 2017 – David R. Gandara, M.D
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December 11, 2017 – Oliver Dorigo, M.D., Ph.D.
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November 01, 2017 – Edward S. Kim, M.D.
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October 25, 2017 – Nadine Barrett, Ph.D.
October 13, 2017 – David Reardon, M.D.
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October 04, 2017 – Garett Frampton
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October 02, 2017 – Yania Jansen
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September 19, 2017 – Jeffrey Weber, M.D., Ph.D.
September 15, 2017 – Renee Cowan
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September 07, 2017 – Martin D. Berger, M.D.
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August 21, 2017 – Donna Cryer
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August 15, 2017 – Richard Boulay, M.D.
July 27, 2017 – Jeffrey Holzbeierlein, M.D.
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January 05, 2017 – Dellann Elliott Mydland
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November 29, 2016 – Ann Culkin, R.N., O.C.N.
November 28, 2016 – Beth Sandy, C.R.N.P
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September 29, 2016 – Mark Malkin, M.D.
September 08, 2016 – Yuhong Dong, M.D., PhD
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Newly Discovered Biomarker May Help Personalize Colorectal Cancer Treatment
Researchers might be on to a new biomarker for patients with colorectal cancer, says Martin D. Berger, M.D., oncologist at the University of Southern California.
BY Martin D. Berger, M.D.
PUBLISHED September 07, 2017
Researchers might be on to a new biomarker for patients with colorectal cancer, says Martin D. Berger, M.D., oncologist at the University of Southern California.
In a phase 3 trial conducted in Europe, 300 patients with metastatic colorectal cancer were assigned a treatment regimen of FOLFIRI plus bevacizumab, while 300 other patients – who had the same staging and type of disease – were given FOLFIRI plus cetuximab. The patients who had the genetic mutation to transport vitamin C had better outcomes and survival on the FOLFIRI plus bevacizumab regimen, while survival for patients with and without this mutation was the same for the group given FOLFIRI and cetuximab.
Findings like these, paired with further investigation, may lead to better personalizing treatment for patients with metastatic colorectal cancer.
Talk about this article with other patients, caregivers, and advocates in the Colorectal Cancer CURE discussion group.