Breast Cancer

The introduction of Tukysa to Kadcyla emtansine significantly improved progression-free survival versus placebo plus Kadcyla in patients with previously treated HER2-positive metastatic breast cancer.

This year, as winter approaches, I’ve been thinking about how I winterize my life and my exercise so that I am ready for more when spring arrives.

Race demonstrated differences in overall survival outcomes, but not for three-year recurrence-free survival in patients with HR-positive, HER2-negative breast cancer, according to data.

The combination of Keytruda to neoadjuvant chemotherapy, followed by Keytruda in combination with endocrine therapy improved pathologic response rates for patients with early-stage, high-risk, estrogen receptor (ER)–positive/HER2-negative breast cancer.

Research is underway on the immune-stimulating antibody conjugate BDC-1001’s effectiveness against HER2-positive cancers when combined with Perjeta, according to data presented at SABCS.

Patients with HR-positive, HER2-negative breast cancer tended to have longer health-related quality of life and improved outcomes with Truqap plus Faslodex, research showed.

The use of artificial intelligence to detect sentinel lymph nodes in patients with breast cancer may be able to save time and reduce costs as compared with immunohistochemistry.

Every holiday season, one song starts to play in my head even if I do not hear it on the radio: “All I Want for Christmas Is My Two Front Teeth.”

Patients with HR-positive HER2-negative advanced breast cancer, including elderly patients, derived a progression-free and overall survival benefit with Kisqali plus endocrine therapy compared with placebo plus endocrine therapy.

Here's what you can be thankful for...

I used my tools as a psychotherapist after being faced with my own cancer diagnosis.

Zotatifin plus Faslodex and Verzenio was granted as a Fast Track Designation for the treatment of ER-positive, HER2-negative advanced or metastatic breast cancer.

The Truqap-Faslodex treatment combination offers “more options” for some patients with HR-positive, HER2-negative breast cancer, an expert told CURE®.

As Shannen Doherty revealed her cancer diagnoses and upcoming podcast and a woman with breast cancer completed her bucket list, here is what’s happening in the oncology space this week.

Patients with metastatic breast cancer receiving HER2-targeted therapies should promptly report any respiratory symptoms or signs of lung and heart disease to their oncology care team to facilitate early intervention and management of side effects.

Patients on HER2-targeted therapies for HER2-positive metastatic breast cancer should be vigilant about potential side effects like heart toxicities and interstitial lung disease and should undergo regular heart function monitoring and lung scans to catch these side effects early.

Imaging scans provide an invaluable method of monitoring response to HER2-positive breast cancer treatment; frequency of imaging scans depends on individual patient response, symptoms, and the need to monitor for side effects such as interstitial lung disease.

HER2-targeted therapies improve outcomes by shutting down growth signaling to cancer cells, targeted delivery of chemotherapy, or blocking intracellular signaling - all leveraging the HER2 receptor to better control metastatic breast cancer.

Treatment for HER2 low metastatic breast cancer may utilize HER2-targeted antibody-drug conjugates like T-DM1 and sacituzumab govitecan after initial therapy; knowing HER2 status, even low expression, is critical to guide use of these HER2-directed ADCs after chemotherapy.

Treatment for HER2-negative metastatic breast cancer depends on factors like hormone receptor status, with chemo/immunotherapy for PD-L1-positive triple negative disease, PARP inhibitors for BRCA mutations, and antibody-drug conjugates as options after first line therapy.

Dr Sara M. Tolaney reviews the currently available treatment options for HER2-positive metastatic breast cancer and notes that many new HER2-targeting antibody-drug conjugates and bispecific antibodies are in development.

Peer- and self-evaluated techniques are being incorporated to improve the sexual health of women with breast cancer.

If metastatic breast cancer no longer responds to a given therapy, finding out what targetable mutations a patient has may guide the next steps for treatment, an expert said.