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Updated Study Results Shows Activity for Keytruda in Gastric Cancer
January 16th 2015Among patients with metastatic gastric cancer treated with the PD-1 inhibitor Keytruda, the agent showed promising activity, according to updated findings from the KEYNOTE-012 study presented at the Gastrointestinal Cancers Symposium.
Integrating PD-1 Inhibitors into the Treatment of Melanoma
January 14th 2015In the past four months, the PD-1 inhibitors Opdivo (nivolumab) and Keytruda (pembrolizumab) have been approved for the treatment of advanced melanoma. Jeffery S. Weber, a senior member at Moffitt Cancer Center in Tampa, Fla., provides insight on what this means for treating patients.
Several Cancer Therapies Up for FDA Review in 2015
January 13th 2015The Food and Drug Administration's calendar for making decisions on new cancer drugs and indications is taking shape for 2015, and the clock is ticking on at least 13 applications for novel agents and new therapeutic settings for existing drugs.
Higher Vitamin D Levels Associated with Higher Survival in Metastatic Colorectal Cancer
January 13th 2015Patients with newly diagnosed metastatic colorectal cancer (mCRC) who had higher levels of vitamin D in their blood lived a median of eight months longer and experienced greater disease-free survival after their cancer treatment, according to research reported at the 2015 Gastrointestinal Cancers Symposium.
Surveillance Could Be a Viable Option for Certain Patients With Rectal Cancer
January 13th 2015A "watch and wait" surveillance approach may allow certain patients with rectal cancer to achieve excellent outcomes without immediate surgery, according to a retrospective review of clinical data presented at the 2015 Gastrointestinal Cancers Symposium.
Study Shows Women with Stage 1 HER2-Positive Breast Cancers Could Benefit from Herceptin
January 10th 2015Results of a phase 2 study showed that women with small, stage 1 HER2-positive breast cancer who received a combination of lower-intensity chemotherapy and Herceptin following surgery were highly unlikely to have a recurrence.
A Q&A with Jack West on Strategies for Personalizing NSCLC Therapy
January 6th 2015As a lung cancer researcher and medical director of the Thoracic Oncology Program at the Swedish Cancer Institute in Seattle, Wash., Howard L. "Jack" West has made communicating with oncology specialists and patients part of his professional mission.
FDA Updates Gazyva Label for Frontline Chronic Lymphocytic Leukemia
December 27th 2014The FDA has updated the label for Gazyva (obinutuzumab) plus chlorambucil to include data from stage 2 of the phase 3 CLL11 study, which detailed an improvement in progression-free survival as a frontline treatment for patients with chronic lymphocytic leukemia.
The Stockings are Hung with Care
December 25th 2014As I count my many blessings, my wish for you is that you are able to hold fast to the moment and breathe in all that you have, all that is dear to you now and that you, too, will fill your stockings with the presence and love of the moment. Wishing you all a very Merry Christmas!
Firstline Kadcyla Results Disappointing in HER2-Positive Metastatic Breast Cancer Trial
December 19th 2014Two HER2-targeting regimens anchored by Kadcyla (T-DM1) failed to outperform the standard strategy of Herceptin plus chemotherapy in women newly diagnosed with advanced HER2-positive breast cancer.