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Combining Fludara (fludarabine), Cytoxan (cyclophosphamide), and Rituxan (rituximab) was safer and produced a higher response than pairing Campath (alemtuzumab) with Fludara and Cytoxan in patients under age 65 with advanced B-cell chronic lymphocytic leukemia receiving their first treatment.

The key findings from a phase 3 Spanish study are three-fold: less aggressive initial (induction) therapy with once-weekly—rather than twice-weekly—Velcade (bortezomib) was effective; melphalan outdid thalidomide as a partner to Velcade; and following induction with maintenance therapy may be the best approach for treating multiple myeloma patients over 65 who haven’t received previous treatment.

Pumping Iron

In the past, doctors advised breast cancer survivors with lymphedema to avoid heavy lifting because of the possibility of infection and symptom flare-ups, but a new study shows weight-lifting may actually be beneficial and help reduce lymphedema symptoms.

One of the most visible side effects of chemotherapy is hair loss—a problem so distressing that some patients refuse treatment to avoid going bald.Studies have suggested that cooling the scalp during and immediately after treatment may help reduce hair loss. When the skin is cold, less blood flows to hair follicles, reducing their exposure to the drugs. One product, the Penguin Cold Cap System (manufactured by Medical Specialties of California UK), is billed as preventing hair loss in 80 percent of patients.