Do You See What I See?
December 08, 2013 – Emily Morrison
Pancreatic Cancer Advocates Unite
December 08, 2013 – Julie Fleshman
Pipeline
December 09, 2013 – Lindsay Ray
The Challenges of Distance Caregiving
December 09, 2013 – Jane Hill
Adult Siblings Often Coordinate Parental Support
December 09, 2013 – Jane Hill
What Could Cause Cognitive Dysfunction after Cancer?
December 09, 2013 – Kathy LaTour
Pharmacologic Approaches to Cognitive Dysfunction
December 09, 2013 – Kathy LaTour
Finding Solutions for Chemobrain
December 08, 2013 – Kathy LaTour
Post-Traumatic Stress Disorder after Childhood Cancer
December 09, 2013 – Don Vaughan
Late Effects & Premature Aging After Pediatric Cancer
December 09, 2013 – Don Vaughan
Health Problems Common in Survivors of Pediatric Cancer
December 09, 2013 – Don Vaughan
Post-Mastectomy Pain Hits a Nerve
December 09, 2013 – Lacey Marlow
Advances in Screening & Early Detection of Pancreatic Cancer
December 09, 2013 – Roxanne Nelson
Changing Course in Pancreatic Cancer
December 09, 2013 – Roxanne Nelson
Tumor Evolution
December 08, 2013 – Katy Human
Solving the Treatment Resistance Riddle
December 09, 2013 – Katy Human
For Caregivers: Tips Before Planning that "End of Treatment" Party
December 09, 2013 – Charlotte Huff
Why Observing Treatment Milestones is an Individual Decision
December 09, 2013 – Charlotte Huff
Searching for an Oncology Surgeon
December 08, 2013 – Katherine Hobson
Is Robot-Assisted Surgery the Best Treatment for Your Cancer?
December 08, 2013 – Katherine Hobson
How I Lost My Uterus and Found My Voice
December 09, 2013 – Kathy LaTour
Personalized Medicine Should Include High-Quality, High-Value Care
December 09, 2013 – Len Lichtenfeld, MD
Website Retooled to Help Visitors Navigate Medicare
December 08, 2013 – Jon Garinn
Poor Kidney Function a Possibility in Adult Survivors of Childhood Cancer
December 09, 2013 – Katherine Lagomarsino
Dispatch: Society for Integrative Oncology's 10th Annual Meeting
December 09, 2013 – Debu Tripathy, MD
Reel Recovery Retreats
December 09, 2013 – Jon Garinn
Studies Confirm Effectiveness of Colorectal Cancer Screening
December 09, 2013 – Elizabeth Whittington
Michael Douglas Reveals He Had Tongue Cancer
December 09, 2013 – Lindsay Ray
Dose of Reality Effective at Stopping Smokers
December 09, 2013 – Lena Huang
FDA's Breakthrough Therapy Designation Aims to Speed Drug Approvals
December 08, 2013 – Susan Jenks
ASH Updates
December 08, 2013 – Elizabeth Whittington
Message From the Editor
December 09, 2013 – Debu Tripathy, MD
Letters From Readers
December 08, 2013
Do You See What I See?
December 08, 2013 – Emily Morrison
Pancreatic Cancer Advocates Unite
December 08, 2013 – Julie Fleshman
Pipeline
December 09, 2013 – Lindsay Ray
The Challenges of Distance Caregiving
December 09, 2013 – Jane Hill
Adult Siblings Often Coordinate Parental Support
December 09, 2013 – Jane Hill
What Could Cause Cognitive Dysfunction after Cancer?
December 09, 2013 – Kathy LaTour
Pharmacologic Approaches to Cognitive Dysfunction
December 09, 2013 – Kathy LaTour
Finding Solutions for Chemobrain
December 08, 2013 – Kathy LaTour
Post-Traumatic Stress Disorder after Childhood Cancer
December 09, 2013 – Don Vaughan
Late Effects & Premature Aging After Pediatric Cancer
December 09, 2013 – Don Vaughan
Health Problems Common in Survivors of Pediatric Cancer
December 09, 2013 – Don Vaughan
Post-Mastectomy Pain Hits a Nerve
December 09, 2013 – Lacey Marlow
Advances in Screening & Early Detection of Pancreatic Cancer
December 09, 2013 – Roxanne Nelson
Changing Course in Pancreatic Cancer
December 09, 2013 – Roxanne Nelson
Tumor Evolution
December 08, 2013 – Katy Human
Solving the Treatment Resistance Riddle
December 09, 2013 – Katy Human
For Caregivers: Tips Before Planning that "End of Treatment" Party
December 09, 2013 – Charlotte Huff
Why Observing Treatment Milestones is an Individual Decision
December 09, 2013 – Charlotte Huff
Searching for an Oncology Surgeon
December 08, 2013 – Katherine Hobson
Is Robot-Assisted Surgery the Best Treatment for Your Cancer?
December 08, 2013 – Katherine Hobson
How I Lost My Uterus and Found My Voice
December 09, 2013 – Kathy LaTour
Personalized Medicine Should Include High-Quality, High-Value Care
December 09, 2013 – Len Lichtenfeld, MD
Website Retooled to Help Visitors Navigate Medicare
December 08, 2013 – Jon Garinn
Currently Viewing
Poor Kidney Function a Possibility in Adult Survivors of Childhood Cancer
December 09, 2013 – Katherine Lagomarsino
Reel Recovery Retreats
December 09, 2013 – Jon Garinn
Studies Confirm Effectiveness of Colorectal Cancer Screening
December 09, 2013 – Elizabeth Whittington
Michael Douglas Reveals He Had Tongue Cancer
December 09, 2013 – Lindsay Ray
Dose of Reality Effective at Stopping Smokers
December 09, 2013 – Lena Huang
FDA's Breakthrough Therapy Designation Aims to Speed Drug Approvals
December 08, 2013 – Susan Jenks
ASH Updates
December 08, 2013 – Elizabeth Whittington
Message From the Editor
December 09, 2013 – Debu Tripathy, MD
Letters From Readers
December 08, 2013
Whole Foods Help Against Cancer
December 07, 2013 – Jeanne Erdmann

Poor Kidney Function a Possibility in Adult Survivors of Childhood Cancer

Long-term and late effects from toxic regimens from childhood cancer treatments include heart damage, lung problems and infertility.

BY Katherine Lagomarsino
PUBLISHED December 09, 2013
As survival rates for many forms of childhood cancer have climbed, more research is uncovering the tolls exacted for life-saving treatments. Long-term and late effects from toxic treatment regimens include heart damage, lung problems and infertility.

A new study from the Netherlands reveals that certain cancer treatments, such as the chemotherapy drugs ifosfamide, cisplatin, carboplatin, high-dose methotrexate and high-dose cyclophosphamide, as well as renal radiation and removal of part or all of the kidney (nephrectomy), can affect a specific type of kidney function in adult survivors of childhood cancer.

The study examined the renal function of 1,122 survivors ages 18 and older. The researchers discovered that the kidney function of those treated with ifosfamide, high-dose cisplatin and nephrectomy began to decline most quickly. Ifosfamide is used to treat lymphomas and sarcomas, while cisplatin is used for retinoblastomas and brain tumors.

The researchers concluded that this long-term effect places survivors at risk for premature kidney failure and recommended that physicians be attentive to those who received some of the more toxic regimens.

Be the first to discuss this article on CURE's forum. >>
Talk about this article with other patients, caregivers, and advocates in the Childhood Cancers CURE discussion group.

Related Articles

1
×

Sign In

Not a member? Sign up now!
×

Sign Up

Are you a member? Please Log In