
New Data Shows Colorectal Cancer is Deadliest Cancer for Adults Under 50
Key Takeaways
- Updated ACS data place colorectal cancer as the top cancer killer in adults under 50, with deaths still increasing while other malignancies decline or stabilize.
- Forecasts suggest a 90% rise in incidence among ages 20–39 by 2030, reinforcing the urgency of earlier risk identification and screening adherence.
Colorectal Cancer Alliance urges action through Project Cure CRC.
The Colorectal Cancer Alliance (Alliance), the nation’s largest nonprofit dedicated to ending the disease, is calling for urgent action following
“Today’s news confirms what experts have been predicting for years, as we witnessed young-onset colorectal cancer rates rising quickly and claiming too many lives,” said Michael Sapienza, CEO of the Colorectal Cancer Alliance. “The Alliance is prepared to meet this moment and propel progress through awareness, screening education, and a renewed commitment to its Project Cure CRC research initiative.”
According to the newly released data, colorectal cancer surpassed other leading malignancies as the number one cause of cancer mortality in adults under 50, and it is the only one where deaths continue to increase.
The Troubling Trend is Steadily Rising
- Incidence among Americans ages 20 to 39 is projected to increase by 90 percent by 2030.
- Every day, almost 60 Americans in their 40s or younger will be diagnosed with colorectal cancer.
- That’s equivalent to a diagnosis in young people every 25 minutes.
The Alliance is working to reverse this grim outlook through Project Cure CRC.
“The discoveries emerging from Project Cure CRC represent the most exciting advances we’ve seen in colorectal cancer research in decades,” said John Marshall, M.D., Chief Medical Consultant, Colorectal Cancer Alliance, and Director, Ruesch Center for the Cure of Gastrointestinal Cancers at Georgetown University. “By strategically investing in bold ideas and brilliant scientists, we’re accelerating the pace of progress toward treatments that patients urgently need.”
For more information on Project Cure CRC, view its recent Curecast, get involved, donate, or learn about submitting a research proposal, visit
Alliance Resources
- Free Helpline: Speak with certified patient and family support navigators at 877-422-2030.
- Free Screening Tool with Symptom & Risk Checker:
getscreened.org - Young-Onset Community & Peer Support:
colorectalcancer.org/resources-support/community-support/young-onset-support
About the Colorectal Cancer Alliance
The Colorectal Cancer Alliance empowers a nation of passionate and determined allies to prevent, treat, and overcome colorectal cancer in their lives and communities. Founded in 1999 and headquartered in Washington, D.C., the Alliance advocates for prevention through initiatives like




