All News


All series


All All News

Some moments in life get seared into your brain. Years later you can picture exactly what you were wearing. You can conjure up the smell of the room.

Second guessing personal medical decisions is common in the world of breast cancer. Is it wrong to rethink some of those choices?

OVER THE LAST FEW years, significant advances were made in the treatment of patients with chronic lymphocytic leukemia (CLL). Several novel therapies, most of them oral, have now been approved by the Food and Drug Administration. These include Imbruvica (ibrutinib), a Bruton’s tyrosine kinase (BTK) inhibitor; Venclexta (venetoclax), a B-cell lymphoma-2 (BCL2) inhibitor; and Zydelig (idelalisib), a phosphoinositide 3-kinase (PI3K) inhibitor.

FDA Approves Opdivo in HCC

By

Opdivo (nivolumab) was granted FDA approval for the treatment of hepatocellular carcinoma (HCC) – regardless of PD-L1 status – for patients who have previously been treated with Nexavar (sorafenib).

Venclexta (venetoclax), a BCL-2 inhibitor, had promising results in patients with relapsed or refractory chronic lymphocytic leukemia (CLL). According to an updated analysis of a clinical trial, the agent led to negative minimal residual disease (MRD) in 40 percent of patients involved.

In a recent phase 2 study, nearly half of patients who had resectable stage 3B/C BRAF V600-mutant melanoma achieved pathologic complete response (pCR) – meaning that no active cancer cells are present – with neoadjuvant combination therapy consisting of Tafinlar (dabrafenib) and Mekinist (trametinib).

In early 2015, Zika outbreaks caused widespread panic in many parts of North and South America. However, now researchers are exploring the possibility of putting the virus to good use: fighting glioblastoma multiforme (GBM), the most deadly type of brain cancer.

At one time, the word “cancer” was only whispered and never spoken out loud. Times change, but sometimes it’s hard to let those you work with know that you have/had cancer.