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Choosing the Right Path
September 30, 2015 – Mike Hennessy, Sr.
Medical Illustration: Prostate Cancer
September 30, 2015 – Pam Curry
Where Are the Men? BRCA Mutations and Male Awareness
September 28, 2015 – Linda Penwarden, MN, RN, AOCN
Surgery or Radiation for Prostate Cancer: What Determines the Choice?
September 25, 2015 – Maureen Salamon
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September 24, 2015 – Roxanne Nelson, RN
Delicate Difference: More Surgical Options for Prostate Cancer
September 24, 2015 – Beverly A. Caley
Satisfaction Guaranteed: Sexual Activity After Prostate Cancer Therapy
September 23, 2015 – Erik Ness
On Guard: Gauging Aggressiveness of Prostate Cancer Aids Decision Making
September 21, 2015 – Jeanne Erdmann
Scanning the Horizon: Advances in Radiation Treatment for Prostate Cancer
September 30, 2015 – Maureen Salamon
Choosing the Right Path
September 30, 2015 – Mike Hennessy, Sr.
Resolving a Controversy: The Value of PSA Screening
September 30, 2015 – Debu Tripathy
Medical Illustration: Prostate Cancer
September 30, 2015 – Pam Curry
Where Are the Men? BRCA Mutations and Male Awareness
September 28, 2015 – Linda Penwarden, MN, RN, AOCN
Surgery or Radiation for Prostate Cancer: What Determines the Choice?
September 25, 2015 – Maureen Salamon
Marathon Men: Living Longer With Prostate Cancer
September 24, 2015 – Roxanne Nelson, RN
Delicate Difference: More Surgical Options for Prostate Cancer
September 24, 2015 – Beverly A. Caley
Satisfaction Guaranteed: Sexual Activity After Prostate Cancer Therapy
September 23, 2015 – Erik Ness
On Guard: Gauging Aggressiveness of Prostate Cancer Aids Decision Making
September 21, 2015 – Jeanne Erdmann
Scanning the Horizon: Advances in Radiation Treatment for Prostate Cancer
September 30, 2015 – Maureen Salamon

Choosing the Right Path

Understanding state-of-the-art care helps patients with prostate cancer to choose treatments
BY Mike Hennessy, Sr.
PUBLISHED September 30, 2015
Longer lives, fewer side effects, less overall toxicity: These are the treatment goals that men tend to share after being diagnosed with prostate cancer.

Although there are still mysteries to resolve, continual advances in treatment mean that these benchmarks are being met more and more effectively over time.

In this special issue of CURE, we bring you a comprehensive overview of the latest techniques in prostate cancer treatment, from the strategies appropriate for the earliest phases of the disease to those applied in the latest stages. In a detailed timeline spanning back to the year 1904, we also offer a sense of just how far prostate cancer treatment has come.

For instance, in slow-growing localized disease, when active surveillance is an option, state-of-the-art imaging in the form of the highly accurate multiparametric MRI is becoming more available. In addition, there’s a growing understanding of biomarkers that can signal the presence of prostate cancer or its aggressiveness, helping to determine when the disease should be actively treated instead of carefully watched.

When men do step into the treatment arena, a prime concern is often finding a way to effectively fight the cancer without incurring the common side effects of urinary incontinence or sexual dysfunction.

For one man featured in these pages, that became possible through highdose- rate brachytherapy; in fact, shorter, higher-dose courses of therapy are being explored throughout the radiation realm. In the surgical suite, more and more doctors are turning to laparoscopic prostatectomy (in some cases robotic) as a less invasive alternative to open prostatectomy, and we also discuss surgical techniques on the horizon that may do more to prevent side effects by avoiding damage to the structures surrounding the prostate.

Perhaps the most notable recent advances in prostate cancer treatment are the six new medical agents approved since 2010, five of them based on their ability to improve patient survival. In addition to presenting information on these cutting-edge treatments, we discuss a variety of investigational drugs, including hormonal treatments galeterone (TOK-001) and ARN-509 and the immunotherapy Prostvac.

In keeping with CURE’s mission to provide both education and inspiration for patients, survivors and caregivers during the cancer journey, we’ve filled this issue with facts and advice about every aspect of prostate cancer screening, diagnosis, treatment and research – and even some thoughts on living with side effects. Through guidance from leading oncologists and other decision-making tools, we hope to leave you better prepared to make choices about your own care – or at least to ask the questions that will help you determine the path that is right for you. As always, thank you for reading.

Mike Hennessy, Sr.
Chairman and CEO
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